February 2019 – Page 2 – REGENHEALTHSOLUTIONS (RHS)

PIER MARIA FORNASARI
2019-02-22

Institute for Clinical and Economic Review’s Assessment Finds Spinraza and Zolgensma Provide Substantial Health Benefits for People with Spinal Muscular Atrophy

Current pricing of Spinraza would require a substantial discount to meet traditional cost-effectiveness ranges; Zolgensma’s value-based price range is between $310,000-$900,000 using standard methodology but as high as $1.5 million using alternative measures of health gain —— As with all treatments for ultra-rare conditions, judgments of overall value require consideration of contextual issues and broader

7 comments InREGENERATIVE MEDICINE

PIER MARIA FORNASARI
2019-02-22

How gut bacteria controls gene expression through “interspecies communication”

Highlights •Microbiome-derived NO promotes widespread S-nitrosylation of the host proteome •Interspecies S-nitrosylation regulates miRNAs, gene expression and host development •Microbiota control host function by shaping the post-translational landscape Summary Bioactive molecules can pass between microbiota and host to influence host cellular functions. However, general principles of interspecies communication have not been discovered. We show here

No Comments InMICROBIOME

PIER MARIA FORNASARI
2019-02-22

RESTORE encourages your contribution to promote the project. Support RESTORE consortium

Advanced Therapies (Advanced Therapies Medicinal Products and Biologised Medical Devices – ATMP/bio-MD) are a potential game changer in health care: They aim to transform the current focus on “treatment of disease” into one that concentrates on “regeneration of health”. The unifying goal of RESTORE is the implementation of newly developed Advanced Therapies in clinical routine

No Comments InRESTORE LARGE SCALE RESEARCH INITIATIVE

PIER MARIA FORNASARI
2019-02-21

‘Off-the-shelf’ CAR-Ts have an important role to play – but are they ready for prime time?

Allogeneic CAR-Ts could serve an important niche – particularly for patients who can’t receive autologous CAR-Ts – but the earliness of the data makes conclusions tough to draw. Since their transition from small, academic clinical trials to commercial production, CAR-T cell therapies have won recognition as a novel and highly effective therapeutic modality, particularly in

One comment InCAR-T

PIER MARIA FORNASARI
2019-02-21

Microsoft, Takeda, Eurordis take on rare diseases in children with report, pilots

The three companies announced a slew of pilots employing machine learning, collaborative digital tools and blockchain technology. A year after Microsoft, Takeda and Eurordis announced that they were teaming up on an innovation initiative to solve the issue of diagnosing children with rare diseases, the partners have unveiled an actionable recommendation report and three new

One comment InARTIFICIAL INTELLIGENCE

PIER MARIA FORNASARI
2019-02-21

Procter & Gamble Partners with Aether to Advance AI-Driven 3D Bioprinting

The 3D printing and AI startup Aether has reached a two-year joint agreement with Procter & Gamble to further develop its AI-driven 3D bioprinting system into an “intelligent robotic craftsman”. Procter & Gamble, the multinational consumer goods giant, has agreed to a two-year developmental agreement with the San Francisco-based 3D printing and AI startup Aether.

8 comments InBIOPRINTING

PIER MARIA FORNASARI
2019-02-21

Researchers define cells used in bone repair

Research led by Johns Hopkins investigators has uncovered the roles of two types of cells found in the vessel walls of fat tissue and described how these cells may help speed bone repair. The study found that one of these perivascular stem cell types, pericytes, induces growth of new blood vessels, while another type, adventicytes,

2 comments InREGENERATIVE MEDICINE

PIER MARIA FORNASARI
2019-02-21

AI applications in healthcare grow, opening channel prospects

The hype around AI applications in healthcare spans decades, but the latest wave of AI tech suggests real-world traction. Artificial intelligence is already promising big things at Massachusetts General Hospital and Brigham and Women’s Hospital in Boston, where researchers have been building machine learning models over the past couple of years. Those models now help

10 comments InARTIFICIAL INTELLIGENCE

PIER MARIA FORNASARI
2019-02-15

Pumping the breaks on data from wearables

Data is pouring in from more than 100 million wearable devices worldwide that can track your steps, sleep patterns, blood pressure, heart rate, energy levels and a whole range of other measures. There’s just one problem, says Dr. Karl Poterack, director of applied clinical informatics at Mayo Clinic: “We don’t know if this data can

14 comments InWEARABLES

PIER MARIA FORNASARI
2019-02-13

RHS is supporting RESTORE large scale research initiative

REGENHEALTHSOLUTIONS is a strong supporter of RESTORE, one of the six large scale research initiatives selected by European Commission in areas from health and energy to artificial intelligence and cultural heritage—to compete to become one of its next billion-euro ‘flagship’ science initiatives. On 1 March, each team will receive €1 million (US$1.1 million) to develop a

5 comments InRESTORE LARGE SCALE RESEARCH INITIATIVE

REGENERATIVE AND PERSONALISED MEDICINE

DIGITAL HEALTHCARE

Archives: 2019-02-22

Institute for Clinical and Economic Review’s Assessment Finds Spinraza and Zolgensma Provide Substantial Health Benefits for People with Spinal Muscular Atrophy

How gut bacteria controls gene expression through “interspecies communication”

RESTORE encourages your contribution to promote the project. Support RESTORE consortium

‘Off-the-shelf’ CAR-Ts have an important role to play – but are they ready for prime time?

Microsoft, Takeda, Eurordis take on rare diseases in children with report, pilots

Procter & Gamble Partners with Aether to Advance AI-Driven 3D Bioprinting

Researchers define cells used in bone repair

AI applications in healthcare grow, opening channel prospects

Pumping the breaks on data from wearables

RHS is supporting RESTORE large scale research initiative