Archives May 2019

Scientists developed a light-activated bio-glue that can seal a heart wound in seconds

A new ‘biological glue’ developed by Chinese researchers could one day stop hearts and arteries from uncontrollable bleeding. Placed on an open wound and activated through UV light, this life-saving sealant rapidly morphs into a non-toxic hydrogel, capable of withstanding both slippery surfaces and the pulsing of heart tissue. The adhesive sealant hasn’t been tested

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Liquid biopsy could identify cancer patients at risk of metastatic disease, offering an opportunity to tailor treatment

Researchers at The Royal Marsden say ctDNA, a form of liquid biopsy, may be an accurate technique to monitor treatment response in patients with locally advanced rectal cancer, allowing treatment to be adapted or changed earlier to try to prevent the development of metastatic disease.  Results from the study, led by researchers at The Royal

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New strategy of reprogramming regulatory T cells may improve cancer therapies

While therapies that harness the power of the immune system against cancer have made remarkable progress against certain types of tumours, they still remain ineffective in most cancer patients. A new study has described a method of reprogramming the regulatory T cells that usually suppress immune responses into inflammatory cells that not only permit but

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Adopting a healthy lifestyle helps reduce the risk of dementia

New WHO Guidelines recommend specific interventions for reducing the risk of cognitive decline and dementia People can reduce their risk of dementia by getting regular exercise, not smoking, avoiding harmful use of alcohol, controlling their weight, eating a healthy diet, and maintaining healthy blood pressure, cholesterol and blood sugar levels, according to new guidelines issued

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RESTORE Large Scale Research Initiative New Fact Sheets and Presentation

Before Kick-off meeting in Berlin, RESTORE Community has published two important presentations which can be downloaded in the website and here we present and attach them. The first is a presentation of the Community Fact sheet. The second is a PowerPoint presentation. OVERVIEW Shifting from treating symptoms to curing chronic diseases by making the transformative

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Preclinical Safety Study of a Combined Therapeutic Bone Wound Dressing for Osteoarticular Regeneration

Investigators tested the preclinical safety of the innovative implant ARTiCAR for the treatment of osteoarticular lesions. Thanks to the combination of two advanced therapy medicinal products, a polymeric nanofibrous bone wound dressing and bone marrow-derived mesenchymal stem cells, the ARTiCAR promoted both subchondral bone and cartilage regeneration. [Nat Commun] The extended life expectancy and the

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Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle

Researchers of the Stanford University College of Medicine have just published an important paper on FAP mesenchymal stromal cells in muscle regeneration. The necessity of mesenchymal stromal cells, called fibroadipogenic progenitors (FAPs), in skeletal muscle regeneration and maintenance remains unestablished. We report the generation of a PDGFRαCreER knockin mouse model that provides a specific means of

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