AI makes retinal imaging 100 times faster, compared to manual method

NIH scientists use artificial intelligence called ‘P-GAN’ to improve next-generation imaging of cells in the back of the eye Researchers at the National Institutes of Health applied artificial intelligence (AI) to a technique that produces high-resolution images of cells in the eye. They report that with AI, imaging is 100 times faster and improves image

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Physical Activity Reduces Stress-Related Brain Activity to Lower Cardiovascular Disease Risk

Key Takeaways New research indicates that physical activity lowers cardiovascular disease risk in part by reducing stress-related signaling in the brain. In the study, which was led by investigators at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, and published in the Journal of the American College of Cardiology, people

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New TRIPOD+AI guidelines reflect growing use of AI in healthcare research

The widespread use of artificial intelligence (AI) in medical decision-making tools has led to an update of the TRIPOD guidelines for reporting clinical prediction models. The new TRIPOD+AI guidelines are launched in the BMJ today. TheTRIPOD guidelines (which stands for Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis Or Diagnosis) were developed in 2015

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Adolescent Idiopathic Scoliosis patients showed pontine hypertrophy and asymmetry of diffusion parameters in the Brain Corticoreticular Pathway

Heavy school bags, poor posture, one-handed sports are often blamed for the development of curved spine in teens. Known as adolescent idiopathic scoliosis (AIS), it affects those aged 10 to 19 but has no known cause. A team from Singapore General Hospital (SGH) and National Neuroscience Institute (NNI) has now discovered that the answer to

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FDA Approves First Gene Therapy for Children with Metachromatic Leukodystrophy

The U.S. Food and Drug Administration approved Lenmeldy (atidarsagene autotemcel), the first FDA-approved gene therapy indicated for the treatment of children with pre-symptomatic late infantile, pre-symptomatic early juvenile or early symptomatic early juvenile metachromatic leukodystrophy (MLD).  Metachromatic leukodystrophy is a debilitating, rare genetic disease affecting the brain and nervous system. It is caused by a

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Mayo Clinic researchers find promise in new potential treatment for liver failure

A new drug has been shown to increase healing and regeneration of the liver after major surgery, according to a study published in the scientific journal Cell. Researchers hope that this could lead to more surgical options for patients diagnosed with advanced liver tumors and liver failure. “This research is significant because this is the first

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A micro-fragmented collagen gel as a stem cell-assembling platform for critical limb ischemia repair

Critical limb ischemia is a condition in which the main blood vessels supplying blood to the legs are blocked, causing blood flow to gradually decrease as atherosclerosis progresses in the peripheral arteries. It is a severe form of peripheral artery disease that causes progressive closure of arteries in the lower extremity, leading to the necrosis

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Preliminary Clinical Trial Results Show ‘Dramatic and Rapid’ Regression of Glioblastoma after Next Generation CAR-T Therapy

A collaborative project to bring the promise of cell therapy to patients with a deadly form of brain cancer has shown dramatic results among the first patients to receive the novel treatment. In a paper published today in The New England Journal of Medicine, researchers from the Mass General Cancer Center, a member of the Mass

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