Category REGENERATIVE MEDICINE

The Human Cell Atlas is an international collaboration of scientists dedicated to mapping all of the cells in the human body

There’s an entire world of cells keeping the human body going — breaking down bits of food, defending us from invaders, and, sometimes, going wonky and wreaking havoc. Now, a group of scientists is conducting a cellular census, surveying every tissue in the human body and finding out what cells actually live there. They’re part

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USC-led advance in groundbreaking cancer treatment eliminates severe side effects

An advance in the groundbreaking cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects, making the treatment safer and potentially available in outpatient settings, a new USC study shows. “This is a major improvement,” said Si-Yi Chen of the USC Norris Comprehensive Cancer Center, professor in the Department of Molecular Microbiology

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Stem cells show promise for acute-on-chronic liver failure

 Promethera Biosciences SA, a global innovator in cell-based medicines and liver diseases, today announced clinical data from the ongoing phase 2a study of its lead product candidate HepaStem® in patients with Acute-on-Chronic Liver Failure (ACLF) or acute decompensation (AD) at high risk of developing ACLF. The data was presented in an oral presentation during the

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Pig brains kept alive outside body for hours after death

Researchers have developed a high-tech support system that can keep a large mammalian brain from rapidly decomposing in the hours after death, enabling study of certain molecular and cellular functions. With funding through the National Institutes of Health BRAIN Initiative, researchers developed a way to deliver an artificial blood supply to the isolated postmortem brain of

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Gene therapy restores immunity in infants with rare immunodeficiency disease

NIH scientists and funding contributed to development of experimental treatment A small clinical trial has shown that gene therapy can safely correct the immune systems of infants newly diagnosed with a rare, life-threatening inherited disorder in which infection-fighting immune cells do not develop or function normally. Eight infants with the disorder, called X-linked severe combined

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The Landscape of Cellular and Gene Therapy Products: Cost, Approvals, and Discontinuations

The past 10 years witnessed a significant increase in the approval of cellular and gene therapy products worldwide. The US Food and Drug Administration (FDA) approved 3 gene therapy products within the last 4 months of 2017. The objective of this study was to examine the approval characteristics, discontinuations and cost of all cellular and

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Two Patients Treated with CRISPRed Cells in Immunotherapy Trial

Researchers have infused cells edited using CRISPR-Cas9 into two patients in a trial conducted at the University of Pennsylvania, NPR reports today (April 16). A university spokesperson confirmed in an emailed statement to The Scientist that the trial is underway and that two patients, one with multiple myeloma and one with sarcoma, have been treated so far. The study is

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Industry updates from the field of stem cell research and regenerative medicine in February 2019

Latest developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from nonacademic institutions in February 2019. Business development Collaborations, partnerships & alliances Collaboration agreement: Pluristem & NASA Pluristem Therapeutics (Israel; www.pluristem.com) has collaborating with the NASA’s Ames Research Center to evaluate the potential of Pluristem’s PLX cell

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