Category REGENERATIVE MEDICINE

Scaffold-free cell patches possible with simple protocol for engineered adipose-derived stem cells

Cell sheets have previously shown greater efficacy for tissue repair than injections of single stem cells. New research conducted by scientists at the Los Angeles Biomedical Research Institute and Emmaus Life Sciences, Inc. (both CA, USA) has demonstrated the possibility of producing scaffold-free engineered cell sheets. These cell ‘patches’ could enable better organ repair follow

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The Magneuron project: remote-controlling cells to cure neurodegenerative diseases

01 MARCH 2019 P.M.Fornasari On average, people are living longer than ever before, and that’s good news. However, ageing populations mean higher rates of certain illnesses, such as neurodegenerative disorders. A prominent example of is Parkinson’s disease, a medical condition that already affects 6.5 million people worldwide. This number is expected to more than double

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The Alliance for Regenerative Medicine Publishes First-Ever Rare Disease Report, Detailing Financial & Clinical Progress of 323 Rare-Disease Focused Cell & Gene Therapy Developers Worldwide

01 March 2019 P.M.Fornasari Rare diseases affect fewer than roughly five in 10,000 people worldwide. Approximately 80% of rare diseases have identified genetic origins, and are often debilitating; about 30% of children with a rare disease will die before their fifth birthday. There are roughly 30 million people in the U.S. living with a rare

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Reprogrammed’ stem cells to treat spinal-cord injuries for the first time

Approval from Japanese regulators means that trials of induced pluripotent stem cells can begin later this year. Scientists in Japan now have permission to inject ‘reprogrammed’ stem cells into people with spinal-cord injuries. An upcoming trial will mark the first time that induced pluripotent stem (iPS) cells have been used to treat spinal-cord injuries, after

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Chronic Low Back Pain Study Results Indicate Benefit With Tanezumab

Februray 25, 2019 P.M. Fornasari Tanezumab, an investigational subcutaneously-administered, non-opioid treatment, may benefit patients with moderate to severe chronic low back pain (CLBP), according to top-line results from a Phase 3 study. Study A4091059, a double-blind, placebo- and active-controlled study, included patients with moderate to severe CLBP who had persistent low back pain for more

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ASIPP Releases Guidelines for Use of Biologics in Management of Low Back Pain

February 25, 2019 P.M. Fornasari A task force of regenerative medicine experts established by the American Society of Interventional Pain Physicians (ASIPP) has formulated new guidelines for the safe and effective use of biologics in the management of low back pain. The guidelines, published in Pain Physician, are based on a review of the literature on the

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FDA Encourages Development of Regenerative Medicines

The agency clarified the process for development programs for regenerative medicine therapies. Feb 20, 2019 By Pier Maria Fornasari FDA provided further details in February 2019 on how manufacturers may use expedited development programs for regenerative medicine therapies, clarifying that the category includes gene and Chimeric antigen receptor T cells (CAR-T) therapies, as well as cellular

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