FDA launches app for healthcare professionals

To report novel uses of existing medicines for patients with difficult-to-treat infectious diseases The US Food and Drug Administration announced the global launch of CURE ID, an Internet-based repository that will allow the clinical community to report their experiences treating difficult-to-treat infectious diseases with novel uses of existing FDA-approved drugs through a website, a smartphone

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FDA sends warning to companies for offering unapproved umbilical cord blood products that may put patients at risk

Liveyon Labs Inc. and Liveyon LLC warned that their stem cell products lack required FDA approval and represent a potential risk to the public health The U.S. Food and Drug Administration has warned Liveyon Labs Inc. (Liveyon Labs) and Liveyon LLC, of Yorba Linda, California, and their presidents and chief executive officers, Roya Panah and John

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Stanford researchers program cancer-fighting cells to resist exhaustion, attack solid tumors in mice

CAR-T cells are remarkably effective against blood cancers, but their effect can be transient as the cells become exhausted. Stanford researchers found a way to keep the cells effective in mice with human tumors. A new approach to programming cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human

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Mesenchymal stem cell perspective: cell biology to clinical progress. Review

The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell population of multipotential stem/ progenitor cells commonly referred to as mesenchymal stem cells, multipotential stromal cells, mesenchymal stromal cells, and mesenchymal progenitor cells. The MSCs can differentiate to important lineages under defined conditions in vitro and in limited

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Novartis’ new cell therapy facility could ease manufacturing squeeze for CAR-T med Kymriah

Novartis’ big push into cell and gene therapy hasn’t been the smoothest of rides, with a data manipulation scandal hamstringing Zolgensma and manufacturing concerns hurting CAR-T cancer therapy Kymriah. Could a new European facility help turn around the latter’s production bottleneck?  Novartis last week opened its newest cell and gene therapy facility in Stein, Switzerland, giving the

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Pfizer, Novartis lead $2 billion spending spree on gene therapy production

Source REUTERS Eleven drugmakers led by Pfizer and Novartis have set aside a combined $2 billion to invest in gene therapy manufacturing since 2018, according to a Reuters analysis, in a drive to better control production of the world’s priciest medicines. The full scope of Novartis’ $500 million plan, revealed to Reuters in an interview

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World first as artificial neurons developed to cure chronic diseases

Artificial neurons on silicon chips that behave just like the real thing have been invented by scientists of the University of Bath and researchers from the Universities of Bristol, Zurich and Auckland – a first-of-its-kind achievement with enormous scope for medical devices to cure chronic diseases, such as heart failure, Alzheimer’s, and other diseases of

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Lactose drives Enterococcus expansion to promote graft-versus-host disease

An international team led by scientists from Memorial Sloan Kettering has shown for the first time that foods containing lactose, a sugar that’s naturally found in milk and dairy products, help Enterococcus thrive in the gut, at least in mice. Infections with the Enterococcus bacterium are a major threat in healthcare settings. They can lead to inflammation

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