Brain disease drug delivery platform developed by researchers

So-called ‘nanodiamonds’ could serve as a platform for diagnostic and therapeutic approaches for neurodegenerative diseases. Scientists at the Max Planck Institute for Polymer Research (MPI-P) have produced tiny diamonds, so-called ‘nanodiamonds’, which could serve as a platform for both the therapy and diagnosis of brain diseases. Led by Dr Jana Hedrich, Professor Heiko Luhmann and

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NIH, Cincinnati Children’s scientists develop potential strategy against leukemia drug resistance

Two-pronged approach stymies AML escape plan, could have applications to many cancers. Scientists from the National Institutes of Health and Cincinnati Children’s Hospital Medical Center have devised a potential treatment against a common type of leukemia that could have implications for many other types of cancer. The new approach takes aim at a way that

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Magenta Therapeutics Announces FDA Regenerative Medicine Advanced Therapy (RMAT) Designation Granted to MGTA-456 for the Treatment of Inherited Metabolic Disorders

 Magenta Therapeutics, a clinical-stage biotechnology company developing novel medicines to bring the curative power of stem cell transplant to more patients, today announced that the U.S. Food and Drug Administration (FDA) granted Regenerative Medicine Advance Therapy (RMAT) designation for MGTA-456, a one-time cell therapy for the treatment of multiple inherited metabolic disorders. “This RMAT designation was based

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Don’t Believe Everything You Hear about Stem Cells

The science is progressing rapidly,but bad actors have co-opted stem cells’ hope and promise by preying on unsuspecting patients and their families Source Scientific American By Deepak Srivastava on September 4, 2019 Stem cell science is moving forward rapidly, with potential therapies to treat intractable human diseases on the horizon.Clinical trials are now underway to test the safety

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Newcastle Hospitals set to transform patient care with new 3D print lab

Orthopaedic and Spinal Surgeons at Newcastle Hospitals NHS Foundation Trust are leading the charge to improve patient care with a new in-house 3D print lab provided by axial3D, a leading medical 3D printing firm in the UK. Newcastle Hospitals will benefit from an on-site 3D printing facility, allowing clinicians immediate access to patient-specific 3D printed models with

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A Comparison of Phenotypic and Functional Properties of Mesenchymal Stromal Cells and Multipotent Adult Progenitor Cells

Both multipotent adult progenitor cells and mesenchymal stromal cells are bone-marrow derived, non-hematopoietic adherent cells, that are well-known for having immunomodulatory and pro-angiogenic properties, whilst being relatively non-immunogenic. The authors compare the phenotypic and functional properties of these two cell types, to help in determining which would be the superior cell type for different applications.

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Ultragenyx Announces Positive Data from Phase 1/2 Study of DTX401 Gene Therapy in Glycogen Storage Disease Type Ia

Increased Time to Hypoglycemia and Reduction in Cornstarch Use in Cohorts 1 and 2; Improvement of Additional Key Metabolic Measures Observed Cohort 1 Patients Continue to Demonstrate Long-Term, Durable Responses Company to Enroll Three Patients in Expansion Cohort to Confirm 6.0 × 10^12 GC/kg Dose as Optimal Dose for Phase 3 Study Ultragenyx Pharmaceutical, a

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This Startup Used AI To Design A Drug In 21 Days

Hong Kong-based Insilico Medicine published research Monday showing that its deep learning system could identify potential treatments for fibrosis. That system, called generative tensorial reinforcement learning, or GENTRL for short, was able to find six promising treatments in just 21 days, one of which showed promising results in an experiment involving mice. The research has been

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OPEN TO THE WORLD: 51 NATIONALITIES AMONG WINNERS OF 2019 ERC STARTING GRANTS

Four hundred and eight early-career researchers have been awarded European Research Council grants in this year’s first completed ERC call for proposals. The highly-coveted funding will help individual scientists and scholars to build their own teams and conduct pioneering research across all disciplines. The grants, worth in total €621 million, are part of the EU’

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Gene Therapy: How ‘Advanced’ is Europe?

Chronicling the EU’s past struggles and new efforts in promoting gene therapies, known in Europe as advanced therapy medicinal products In Europe, legislation relating to medicines based on genes, tissues, or cells dates back nearly 20 years, and was reinforced by specific European Union regulation that came fully into effect nearly a decade ago—but still today

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