Researchers at the National University of Singapore have developed artificial skin that almost works as well as the human one.

A team of scientists has managed to develop an electronic artificial skin that mimics that of humans. The new electronic skin can detect a range of tactile stimuli, such as temperature, pressure or object slippage in milliseconds without compromising accuracy or precision. It can also be used when partially damaged! The research team, from the National University

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The Mitochondrion as an Emerging Therapeutic Target in Cancer

Source https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(19)30171-6 Mitochondria display a dynamic and heterogeneous phenotype that facilitates the metabolic heterogeneity and plasticity of cancer cells. The altered metabolic functions and dynamics of mitochondria in cancer cells, as well as mitochondrial evasion of apoptosis, provide targets for novel cancer therapeutics. The mitochondrial network has distinct morphological features that appear to be interrelated

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ATMP Business and Clinical Updates

Source ARM Atara Biotherapeutics Announces Pricing of $150M Public OfferingJuly 18, 2019 – (Atara Biotherapeutics) – The offering is expected to close on or about July 23, 2019, subject to customary closing conditions. MilliporeSigma and Broad Institute Announce CRISPR License Framework to Encourage InnovationJuly 18, 2019 – (MilliporeSigma) – MilliporeSigma and the Broad Institute of MIT and Harvard

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Leading Innovation The UK’s ATMP Landscape New report

The Alliance for Regenerative Medicine (ARM) and UK BioIndustry Association (BIA) released a collaborative report offering an in-depth look at ATMP sector trends and metrics in the UK. The report details industry-specific statistics compiled from 56 cell therapy, gene therapy, tissue engineering, and other ATMP developers headquartered in the UK, including total financings, partnerships and other deals, clinical

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ILLUMINATING THE BRAIN WARREN ALPERT FOUNDATION AWARD GOES TO FOUR SCIENTISTS FOR SEMINAL DISCOVERIES IN OPTOGENETICS

Harnessing light and genetics, the approach illuminates and modulates the activity of neurons, enables study of brain function and behavior, sets stage for optogenetic therapies The 2019 Warren Alpert Foundation Prize has been awarded to four scientists for pioneering work in the field of optogenetics, a revolutionary technique that uses light and genetic modification to

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Neuralink wants to test brain-reading implants in paralyzed patients next year

In front of a crowd of techies packed into a planetarium, Elon Musk strode out on stage, waxed philosophical about achieving symbiosis with artificial intelligence, and made his latest ambitious pronouncement in a career that’s been full of them: His startup Neuralink has developed technology meant to be implanted into the brain that’s designed to

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Surgical and tissue engineering strategies for articular cartilage and meniscus repair

Source https://www.nature.com/articles/s41584-019-0255-1 Injuries to articular cartilage and menisci can lead to cartilage degeneration that ultimately results in arthritis. Different forms of arthritis affect ~50 million people in the USA alone, and it is therefore crucial to identify methods that will halt or slow the progression to arthritis, starting with the initiating events of cartilage and

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Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction

Since both myocardium and vasculature in the heart are excessively damaged following myocardial infarction (MI), therapeutic strategies for treating MI hearts should concurrently target both so as to achieve true cardiac repair. Here we demonstrate a concomitant method that exploits the advantages of cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) and human mesenchymal

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Induced Pluripotent Stem Cell (iPSC)–Derived Lymphocytes for Adoptive Cell Immunotherapy: Recent Advances and Challenges

The advancement of adoptive cell immunotherapy and the impressive clinical outcomes obtained targeting hematologic malignancies with CAR-T cells dictate for further developments towards a broader use of cellular therapeutics for more patients and more types of malignancy. The advent of iPSC technology provides new perspectives for the manufacturing of customized, tumor-targeting T/NK cells, with improved

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