Athenex, Inc., a global biopharmaceutical company dedicated to the discovery, development and commercialization of novel therapies for the treatment of cancer and related conditions, today announced that it has received Orphan Designations from the European Commission (EC) for paclitaxel and encequidar (“Oral Paclitaxel”) for the treatment of soft tissue sarcoma, following a positive opinion from the

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Combination therapy with BRAF and MEK inhibitors conferred significant PFS benefit compared with BRAF inhibitor monotherapy among patients with metastatic melanoma with rare BRAF mutations or translocations, according to results of an international, retrospective study published in Journal of Clinical Oncology. “Patients with rare BRAF mutations may respond to targeted therapy, however, efficacy seems to be lower compared with patients

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The results, published in the current issue of Scientific Reports, showcase dramatic improvements in light-activated fluorescent dyes for disease diagnosis, image-guided surgery and site-specific tumor treatment. Scientific breakthroughs don’t always happen in labs. For Sophia and Richard Lunt, Michigan State University researchers, many of their breakthroughs happen during neighborhood walks. The married couple’s step-by-step approach

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UNC Lineberger’s Timothy Gerson, MD, PhD, and colleagues have identified a potential approach to stop the growth of the most common type of brain tumor in children. Their research was published in the journal Development. UNC Lineberger’s Timothy Gerson, MD, PhD and colleagues reported in the journal Development that by blocking a signal called GSK-3, they could control tumor

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Researchers from Stowers Institute for Medical Research in Kansas City, MO have identified proteins that are involved in tumor growth and metastasis in many cancers such as breast cancer. The research was published in Science Advances on October 23. Breast cancer is one of the many types of cancer that can be caused by gene alterations of

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Source NIH Director’s Blog Exercise can work wonders for your health, including strengthening muscles and bones, and boosting metabolism, mood, and memory skills. Now comes word that staying active may also help to lower your odds of developing cancer.  After reviewing the scientific evidence, a panel of experts recently concluded that physical activity is associated with reduced

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Cancer cells are masters at avoiding detection, but a new system developed by Yale scientists can make them stand out from the crowd and help the immune system spot and eliminate tumors that other forms of immunotherapies might miss, the researchers report Oct. 14 in the journal Nature Immunology. The new system reduced or eliminated

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Source: H. Lee Cancer Center & Research Institute Patients with advanced melanoma have been able to live longer because of several newly approved targeted treatment options, including BRAF and MEK inhibitors. However, patients will often have different responses to the same treatment due to genetic variability. Melanoma varies from patient to patient, but genetic variability is

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Novel immunotherapy extends therapy now used in fighting leukemia, Tel Aviv University researchers say There is now a multitude of therapies to treat cancer, from chemotherapy and radiation to immunotherapy and small molecule inhibitors. Chemotherapy is still the most widely used cancer treatment, but chemotherapy attacks all the rapidly dividing cells that it locates within

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Source Cancer Network Several promising drugs for the treatment of lung cancer have been garnering attention over recent years. These new treatments have been highlighted at conferences and are sure to impact the standard of care. Some of these new treatments are detailed below. LOXO-292 Various multikinase inhibitors (MKI) with some activity against RET have

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