In Mice: Transplanted Brain Stem Cells Survive Without Anti-Rejection Drugs

By exploiting a feature of the immune system, researchers open the door for stem cell transplants to repair the brain. In experiments in mice, Johns Hopkins Medicine researchers say they have developed a way to successfully transplant certain protective brain cells without the need for lifelong anti-rejection drugs. A report on the research, published Sept. 16 in

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SanBio Granted Regenerative Medicine Advanced Therapy Designation from the U.S. FDA for SB623 for the Treatment of Chronic Neurological Motor Deficits Secondary to Traumatic Brain Injury

The SanBio Group, a scientific leader in regenerative medicine for neurological disorders, today announced that the U.S. Food and Drug Administration (FDA) has granted Regenerative Medicine Advanced Therapy (RMAT) Designation for SB623 cell therapy for the treatment of chronic neurological motor deficits secondary to traumatic brain injury (TBI). The designation is based on clinical results

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Phase I/II Study of Safety and Preliminary Efficacy of Intravenous Allogeneic Mesenchymal Stem Cells in Chronic Stroke

Background and Purpose— Stroke is a leading cause of long-term disability. Limited treatment options exist for patients with chronic stroke and substantial functional deficits. The current study examined safety and preliminary efficacy estimates of intravenous allogeneic mesenchymal stem cells in this population. Methods— Entry criteria included ischemic stroke >6 months prior and substantial impairment (National

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Brain disease drug delivery platform developed by researchers

So-called ‘nanodiamonds’ could serve as a platform for diagnostic and therapeutic approaches for neurodegenerative diseases. Scientists at the Max Planck Institute for Polymer Research (MPI-P) have produced tiny diamonds, so-called ‘nanodiamonds’, which could serve as a platform for both the therapy and diagnosis of brain diseases. Led by Dr Jana Hedrich, Professor Heiko Luhmann and

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Cerebral organoids produce complex brain waves similar to newborns’

Source STAT The Lilliputian versions of human brains that scientists have grown in lab dishes have developed distinct structures such as the hippocampus, grown glia and other cells like those in actual brains, and produced a diverse menagerie of neurons that connect with each other and carry electrical signals. Now scientists have grown hundreds of cerebral organoids

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