In calcium-replete older women, calcium supplements had little effect on the response to antiresorptives, whereas low protein intake blunted their benefits.
In older women with adequate calcium intake receiving osteoporosis medications, calcium supplements did not provide additional improvements in hip bone mineral density (BMD) or bone strength. However, a low dietary protein intake was associated with reduced skeletal benefits of antiresorptive therapy. METHODOLOGY TAKEAWAY IN PRACTICE “[The study] findings do not support the routine use of CaS [calcium