Neuropathy, the nerve damage that causes pain and numbness in the feet and hands and can eventually lead to falls, infection and even amputation, is very common and underdiagnosed, according to a study published in the May 8, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. “More than one-third
Researchers from the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute, led by Dr. Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene -APOE4
Key Takeaways New research indicates that physical activity lowers cardiovascular disease risk in part by reducing stress-related signaling in the brain. In the study, which was led by investigators at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, and published in the Journal of the American College of Cardiology, people
Heavy school bags, poor posture, one-handed sports are often blamed for the development of curved spine in teens. Known as adolescent idiopathic scoliosis (AIS), it affects those aged 10 to 19 but has no known cause. A team from Singapore General Hospital (SGH) and National Neuroscience Institute (NNI) has now discovered that the answer to
In a study published in Cell on March 5, Prof. ZHANG Xiaoming at the Shanghai Institute of Immunity and Infection (SIII) of the Chinese Academy of Sciences and Profs. GAO Qiang, FAN Jia and YANG Li at Fudan University have uncovered an unexpected level of complexity hidden within neutrophils, which were previously thought to be a relatively uniform population
There has been a lot of talk about pollution these days, a phenomenon that is also bad for the heart. But how? An Italian study, the first to have identified the presence of microplastics directly in human arteries, highlights a previously underestimated aspect. After finding them in humans in several organs and tissues, including the
The results of a phase II study with the RNAi therapeutic zilebesiran have appeared in the specialist journal “JAMA”. Accordingly, injections of the drug every three or every six months lower blood pressure sustainably. Zilebesiran is a substance that exerts its pharmacological effect via RNA interference (RNAi) . The active ingredient is a short RNA section that, as small
An experimental drug designed to block blood-clotting proteins may lower the risk of recurrent strokes, according to a dose-finding trial published in The Lancet Neurology. More than 795,000 people in the United States each year suffer a stroke, according to the American Heart Association, and nearly one in five will go on to experience another stroke. “When patients
Glaucoma remains one of the most common causes of vision loss and blindness in the U.S. and much of the world, disproportionately affecting older people, African Americans, and Hispanics and Latinos. Early signs of glaucoma can vary, from eye pressure to changes in the appearance of the optic nerve, and the disease can progress for
Researchers at the University of Leicester have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery, which has just been published in the journal Science opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives. The research, conducted with colleagues
