Five years after a landmark result in a single patient, new findings from the first treated cohort show that optogenetic vision restoration can work beyond an individual case. Scientists have taken another important step toward restoring vision in people with certain inherited forms of blindness. In a study published in the New England Journal of
Researchers identify additional gene controlling production of fetal hemoglobin Harvard Medical School researchers at Boston Children’s Hospital and Dana-Farber Cancer Institute have identified a new pathway that regulates the production of fetal hemoglobin, a form of hemoglobin that normally gets replaced soon after birth by adult hemoglobin. Two FDA-approved gene therapies reactivate the production of
Retatrutide treatment results in substantial weight loss among patients with obesity, as well as reduced pain in patients with knee osteoarthritis and reduced apnea-hypopnea events in patients with obstructive sleep apnea, according to the TRIUMPH-1 study.1 Earlier phase 2 trials including patients with obesity have indicated that once-weekly subcutaneous retatrutide resulted in substantial weight reductions
A new study led by Stanford Medicine found the brain is two separate organs adjacent to one another. The finding could aid research into devastating neurological diseases. For centuries, scientists have thought of the brain as a single, unified organ. But new research led by Stanford Medicine reveals that what we call the brain is
PANXEON, which combines multiple biomarkers, also identified a precancerous condition of the pancreas, potentially opening a path to intervention before invasive cancer develops One reason pancreatic cancer remains so deadly is because it’s usually discovered late, after it has spread. Now, a major new study shows that a blood test developed by researchers led by
Ultra thin, flexible interface locates alternative signal pathways to bypass affected area Researchers from Houston Methodist and the University of Cambridge have developed a flexible device that wraps around the spinal cord and can simultaneously interpret multiple signals related to movement, sensation and internal body functions. The research demonstrates that a single device may be
Researchers developed an innovative therapy that reduces nerve cell damage after spinal cord injury and restored up to 80% of motor function in animal models A new study led by Tel Aviv University offers real hope to millions worldwide affected by spinal cord injury (SCI), a devastating condition in which damage continues to spread after
The kidney function thresholds currently used to diagnose chronic kidney disease reflect an actual increase in the risk of serious disease, according to a study from Karolinska Institutet and Leiden University Medical Center published in the journal JAMA. The researchers also show that risk assessment becomes more accurate when two common blood tests, creatinine and
Mass General Brigham researchers identify conserved gene expression signatures linked to biological aging and risk of disease and mortality, offering a new framework for quantifying aging and evaluating interventions that modulate healthspan and lifespan A team led by investigators at Mass General Brigham has discovered that different tissues in humans and other mammals share common gene expression
Summary The oral medication avatrombopag proved highly effective against chemotherapy-induced thrombocytopenia (CIT) in a phase 2 clinical trial of patients with gastrointestinal cancers. CIT is a major burden in cancer treatment and can cause treatment delays that significantly impact patients’ outcomes. The senior author of the study is Sylvester’s chief of the classical hematology service,
