Physical Activity Reduces Stress-Related Brain Activity to Lower Cardiovascular Disease Risk

Key Takeaways New research indicates that physical activity lowers cardiovascular disease risk in part by reducing stress-related signaling in the brain. In the study, which was led by investigators at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, and published in the Journal of the American College of Cardiology, people

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Adolescent Idiopathic Scoliosis patients showed pontine hypertrophy and asymmetry of diffusion parameters in the Brain Corticoreticular Pathway

Heavy school bags, poor posture, one-handed sports are often blamed for the development of curved spine in teens. Known as adolescent idiopathic scoliosis (AIS), it affects those aged 10 to 19 but has no known cause. A team from Singapore General Hospital (SGH) and National Neuroscience Institute (NNI) has now discovered that the answer to

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Zilebesiran RNAi therapeutic lowers blood pressure for months

The results of a phase II study with the RNAi therapeutic zilebesiran have appeared in the specialist journal “JAMA”. Accordingly, injections of the drug every three or every six months lower blood pressure sustainably. Zilebesiran is a substance that exerts its pharmacological effect via RNA interference (RNAi) . The active ingredient is a short RNA section that, as small

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New Anti-Blood Clotting Drug May Lower Risk of Recurrent Strokes

An experimental drug designed to block blood-clotting proteins may lower the risk of recurrent strokes, according to a dose-finding trial published in The Lancet Neurology. More than 795,000 people in the United States each year suffer a stroke, according to the American Heart Association, and nearly one in five will go on to experience another stroke. “When patients

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Patients with high levels of triglycerides and diglycerides in blood samples are more likely to develop glaucoma

Glaucoma remains one of the most common causes of vision loss and blindness in the U.S. and much of the world, disproportionately affecting older people, African Americans, and Hispanics and Latinos. Early signs of glaucoma can vary, from eye pressure to changes in the appearance of the optic nerve, and the disease can progress for

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Ground-breaking discovery could pave the way for new therapies to prevent cardiovascular disease and stroke

Researchers at the University of Leicester have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery, which has just been published in the journal Science opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives. The research, conducted with colleagues

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Transcatheter Arterialization of Deep Veins in Chronic Limb-Threatening Ischemia can avoid amputation

A study published in the New England Journal of Medicine has shown that there may finally be an alternative to amputation for patients suffering from chronic limb-threatening ischemia (CLTI), the most severe form of peripheral artery disease. This study, co-led by University Hospitals (UH) Harrington Heart & Vascular Institute, could lead to the first FDA approval of

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