Archives: 2026-03-30

New Regimen with Aurora kinase A inhibitor Protects Against Cancer Relapse, Graft-Versus-Host Disease After Donor Stem Cell Transplant

Results of a phase 1 clinical trial show that patients who undergo a blood stem cell transplant involving a donor have a lower risk of relapse and lower rates of graft-versus-host disease when they receive the targeted therapy VIC-1911 along with the standard-of-care regimen that includes post-transplant cyclophosphamide and sirolimus. Led by Shernan Holtan, MD, Chief of Blood

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American College of Cardiology Scientific Statement Highlights Emerging Role of Gene Editing in Cardiovascular Care

A new ACC Scientific Statement outlines the rapidly evolving landscape of gene-editing therapies and their growing relevance to cardiovascular disease, offering clinicians an overview of both the promise and the challenges of this transformative technology. Advances in genome sequencing have dramatically expanded access to genetic testing, improving availability while reducing cost. At the same time, technological

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Targeted Cholesterol-Lowering Therapy Can Prevent First Heart Attack or Stroke in High-Risk Patients with Diabetes

Mass General Brigham researchers found that the intensive cholesterol‑lowering therapy evolocumab reduced the risk of a first major cardiovascular event in high‑risk patients who did not have known atherosclerosis (the build-up of plaque inside artery walls) but did have diabetes. Results were presented at the American College of Cardiology’s Annual Scientific Session & Expo and

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Surviving sepsis: New guidelines harness life saving evidence for treating adults

Updated recommendations include critical insights from research An international team of experts recently came together to update sepsis care guidelines for adults for the first time since 2021. The updates have profound implications for the management of sepsis, which is responsible for approximately 11 million deaths per year worldwide. Co-led by University of Michigan’s Hallie Prescott, M.D.,

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Long Dismissed in Adult Health, the Thymus May Be Critical for Longevity and Cancer Treatment

Mass General Brigham researchers used artificial intelligence to analyze routine medical scans, uncovering how the thymus impacts aging, cardiovascular risk, cancer incidence, and response to immunotherapy. Two new studies from investigators at Mass General Brigham challenge a decades-old assumption that the thymus, an organ best known for its role in establishing immune function in childhood, becomes irrelevant

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Extra belly weight, not BMI, is a stronger predictor of heart failure risk, inflammation: Study

New research suggests that measures of excess weight around the waist (central obesity or visceral fat) may increase the risk of heart failure primarily due to inflammation, according to findings presented at the American Heart Association’s EPI|Lifestyle Scientific Sessions 2026, held in Boston, March 17–20. In this study, researchers found that measurements of higher levels of

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Development of Build Better Bones: A Global Resource for Osteoporosis Self Management

New publication outlines the stakeholder-driven, evidence-based process behind a global, multilingual platform for people living with osteoporosis and their caregivers. A new paper published in Osteoporosis International describes the rigorous, user-centered development of “Build Better Bones,” a multilingual website created to support self-management for people living with osteoporosis and their care partners. Developed by the International Osteoporosis

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American College Cardiology and American Heart Association Release New Clinical Guideline For Managing Dyslipidemia

The new ACC/AHA Guideline on the Management of Dyslipidemia offers a comprehensive “one-stop shop” for addressing the evaluation, management and monitoring of individuals with dyslipidemias, including high blood cholesterol, hypertriglyceridemia, and elevated lipoprotein(a) (Lp[a]). The document consolidates evidence-based recommendations for managing dyslipidemias and retires and replaces the 2018 Guideline on the Management of Blood Cholesterol. Read the full

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Revealing How Transplanted Neural Stem Cells Preserve Vision

Cedars-Sinai investigators working to optimize a cell-based treatment for retinitis pigmentosa have uncovered how transplanted neural stem cells interact with host retinal cells to preserve vision. The findings, published in Nature Communications, may guide future research toward strategies to treat degenerative eye disease. “We used single-cell analysis to show that neural stem cells can protect vision in

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America Academy of Neurology issues guidance on the use of wearable devices

Article examines smart watches, fitness trackers and more for neurological care Highlights: The AAN has issued new guidance on wearable devices and digital apps as potential tools in neurological care, focusing on non-FDA cleared technology. Wearable devices and digital apps that are available to consumers are emerging as potential tools in neurological care. These include

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