A large, diverse cohort study shows that muscle strength, especially grip strength, may signal survival odds in older women, regardless of how much they move, how long they sit, or their measured fitness level. A recent study in JAMA Network Open examined whether muscular strength is associated with mortality in older women, controlling for aerobic activity, sedentary time,
Washington State University researchers have developed a 3D-printed model of the left side of the heart that contracts and beats, offering the chance for surgeons and medical students to rehearse important heart surgeries on a model that acts like the real thing. The WSU researchers, in fact, did a valve repair on their heart model, using ultrasound imaging
A study published today in Stem Cell Reports demonstrates that genetically engineered human pluripotent stem cells (hPSCs) can overcome immune rejection in mice with humanized immune systems, surviving for five months in a stringent transplantation model. The findings provide proof-of-principle for the development of a potential universal donor hPSC line designed to resist immune attack. Led by Danny Chan,
Study reveals how the same molecules that promote healthy aging can fuel cancer growth through distinct molecular pathways Polyamines, a group of naturally occurring molecules found in all living organisms, are essential for fundamental cellular processes, such as growth and differentiation. In recent years, these compounds (particularly spermidine) have gained attention as promising ‘geroprotectors’ that
On Dec 19, 2025, the US Food and Drug Administration (FDA) announced a major milestone by qualifying total hip bone mineral density (BMD), assessed by dual-energy X-ray absorptiometry, as a surrogate endpoint for fractures in phase 3 trials of investigational drugs in postmenopausal women with osteoporosis. The qualification was based on data generated by the
