Even Modest Amounts of Physical Activity May Slow Alzheimer’s Disease Among At-Risk Older Adults

Increasing your steps by even a little bit may help slow down the progression of Alzheimer’s disease among people at heightened risk, according to a new study. In a paper published in Nature Medicine, Mass General Brigham researchers found that physical activity was associated with slower rates of cognitive decline in older adults with elevated levels of

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3D printing ‘glue gun’ can generate bone grafts directly onto fractures

Scientists have developed a tool made from a modified glue gun that can 3D print bone grafts directly onto fractures and defects during surgery. The tool, described in the journal Device, has been tested in rabbits to quickly create complex bone implants without the need for prefabricating in advance. What’s more, the team optimized the 3D-printed grafts for high structural

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Blood Test Could Streamline Early Alzheimer’s Detection

New study findings could make it easier to diagnose Alzheimer’s and related dementias, particularly in underrepresented populations In a landmark study of Hispanic and Latino adults, researchers at University of California San Diego School of Medicine have identified a link between self-reported cognitive decline and blood-based biomarkers, which could pave the way for a simple

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New research highlights critical role of movement in lifelong bone health

Reducing sedentary behaviour and increasing physical activity found to protect against bone loss and fractures across all ages. A new review by the International Osteoporosis Foundation (IOF) Rehabilitation Working Group underscores the powerful impact of lifestyle behaviours—specifically physical activity and sedentary behaviour —on bone health across the human lifespan.  While exercise has long been recognized

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Research for stronger bones and muscles in old age

When GPR133 is activated in bone tissue, it triggers a signal that stimulates bone-forming cells (osteoblasts) and inhibits bone-resorbing cells (osteoclasts). Osteoblasts are specialised bone cells responsible for building and regenerating bone tissue. Researchers at Leipzig University have shown in a high-profile study that a specific receptor plays a key role in the strength of

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The Immunological Landscape of Megakaryocytes: Unveiling New Insights

Megakaryocytes (MKs) are traditionally recognized for their crucial role in platelet production, which is vital for hemostasis and coagulation. However, recent studies have illuminated their far-reaching involvement in immune responses within both physiological and pathological environments. Advances in immunology and cellular biology have revealed the significant immunomodulatory functions of MKs, changing our understanding from their

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Toward better surgical outcomes in patients undergoing knee replacement surgery

Evidence from a questionnaire administered to postoperative patients could settle an ongoing debate regarding best practices in total knee arthroplasty. When performing knee replacement surgery, also called total knee arthroplasty, doctors traditionally try to align the hip, knee, and ankle in a straight line, forming a neutral alignment, rather than replicating the patient’s original alignment.

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The cause of Guillain-Barré syndrome elucidated

Guillain-Barré syndrome is a rare disease in which the immune system attacks the peripheral nerves. Those affected suffer from muscle weakness and paralysis. A research team led by ETH Zurich has now elucidated the mechanism of this autoimmune reaction. Patients with Guillain-Barré syndrome (GBS) suffer from a rare and diverse disorder of the peripheral nervous

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UN agencies warn women and newborns bearing the brunt of the conflict in Gaza: WHO confirms

Women, children and newborns in Gaza are disproportionately bearing the burden of the escalation of hostilities in the occupied Palestinian territory, both as casualties and in reduced access to health services, warn the United Nations Children’s Fund (UNICEF), the United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA), the United Nations

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