Key Takeaways A blood test for the biomarker phosphorylated tau 217 (p-tau217) recently received federal clearance, but questions have emerged around the extent to which such tests can accurately predict whether a cognitively healthy individual will go on to develop cognitive impairment—a key symptom of Alzheimer’s disease. A new, international study involving researchers across three
Researchers found that bacteria linked to gum disease may help drive the development of calcific aortic valve stenosis by triggering inflammation and calcium buildup in the heart valve. The early findings suggest that keeping gums healthy could play a role in reducing the risk of this serious heart condition. Bacteria that cause gum disease may
A study published in The BMJ reveals that most obesity medications do not significantly improve quality of life and few show cardiovascular benefits. In an article by Ingrid Torjesen, a journalist at the British Medical Journal, published on The BMJ website, she explains that drugs used to treat obesity , such as semaglutide (Wegovy) and tirzepatide (Mounjaro),
Researchers at the University of Basel have developed a small dental robot that could automatically prepare teeth for crowns in the future. This would reduce the number of appointments required per dental treatment. The check-up at the dentist ends with bad news: tooth decay has eaten a large hole in the tooth, requiring a crown.
Recommendations for calcium and vitamin D supplementation should be re-evaluated, suggest researchers Calcium, vitamin D, or combined supplements offer little to no clinically meaningful benefit on fracture and fall prevention in most older people, finds an in-depth review of the latest evidence published by The BMJ . Almost a third of people aged 65 and older fall each year,
Low back pain affects around 619 million people worldwide, but a new review suggests many are receiving unnecessary scans and ineffectual treatments. Researchers compiled latest evidence from hundreds of studies to provide clinicians with an up-to-date guide to assist with assessment and management, with “Low Back Pain: A Review” published in JAMA. Professor James McAuley and Dr Aidan Cashin
Researchers developed an innovative therapy that reduces nerve cell damage after spinal cord injury and restored up to 80% of motor function in animal models A new study led by Tel Aviv University offers real hope to millions worldwide affected by spinal cord injury (SCI), a devastating condition in which damage continues to spread after
The kidney function thresholds currently used to diagnose chronic kidney disease reflect an actual increase in the risk of serious disease, according to a study from Karolinska Institutet and Leiden University Medical Center published in the journal JAMA. The researchers also show that risk assessment becomes more accurate when two common blood tests, creatinine and
At the ASCO annual meeting, Dana-Farber’s Brian Wolpin, MD, MPH, will present positive results from the RASolute 302 trial showing a substantial prolongation of survival for patients with previously treated metastatic pancreatic cancer, regardless of RAS mutation status, taking daraxonrasib, an investigational oral RAS(ON) multi-selective inhibitor, compared with chemotherapy. A shift in the way people
Mass General Brigham researchers identify conserved gene expression signatures linked to biological aging and risk of disease and mortality, offering a new framework for quantifying aging and evaluating interventions that modulate healthspan and lifespan A team led by investigators at Mass General Brigham has discovered that different tissues in humans and other mammals share common gene expression
