Scientists from the University of Birmingham have shown an existing drug may reduce damage after spinal cord injury, by blocking the inflammatory response in the spinal cord. Their research, published today in Clinical and Translational Medicine, demonstrates that AZD1236, a drug developed by AstraZeneca, can significantly reduce “secondary damage” caused by the body’s response to spinal
In severe covid-19 and long-term covid, disorders of blood coagulation often occur. Now, researchers at LiU have discovered that the body’s immune system can affect the nail protein on the surface of the sars-cov-2 virus so that it forms misfolded protein, so-called amyloid. The findings point to a possible link between harmful amyloid formation and covid-19 symptoms.
Glioblastomas (GBMs) are highly aggressive cancerous tumors of the brain and spinal cord. Brain cancers like GBM are challenging to treat because many cancer therapeutics cannot pass through the blood-brain barrier, and more than 90 percent of GBM tumors return after being surgically removed, despite surgery and subsequent chemo- and radiation therapy being the most
The inflammatory disorders share similar underlying molecular patterns, a UC San Diego study reports; findings may improve disease diagnosis and treatment and support new drug targets for MIS-C The emergence of COVID-19 had doctors racing to define and treat the new disease, but they soon discovered it was not the only novel illness caused by
Soaring food prices driven by the war in Ukraine and pandemic-fuelled budget cuts set to drive up both need for, and cost of life-saving therapeutic food treatment, the latter by up to 16 per cent The number of children with severe wasting was rising even before war in Ukraine threatened to plunge the world deeper
Research team makes mind-reading possible with electronics and AI University of Minnesota Twin Cities researchers have developed a more accurate, less invasive technology that allows amputees to move a robotic arm using their brain signals instead of their muscles. Many current commercial prosthetic limbs use a cable and harness system that is controlled by the
Patients with severe COVID-19 who were given imatinib had lower mortality rates at 90-day follow-up, according to research published at the ATS 2022 international conference. The study investigated the long-term efficacy of imatinib in hospitalized COVID-19 patients in the Netherlands as part of the randomized, double-blind, placebo-controlled CounterCOVID study. A tyrosine kinase inhibitor, imatinib is currently an oncology
Using machine learning, researchers find patterns in electronic health record data to better identify those likely to have the condition. Long COVID is marked by wide-ranging symptoms, including shortness of breath, fatigue, fever, headaches, “brain fog” and other neurological problems. Such symptoms can last for many months or longer after an initial COVID-19 diagnosis. One
Recently, there have been reports of children with a severe acute form of hepatitis in the UK, Europe, the USA, Israel, and Japan. Most patients present with gastrointestinal symptoms and then progress to jaundice and, in some cases, acute liver failure. So far, no common environmental exposures have been found, and an infectious agent remains
Researchers at Karolinska Institutet, Technical University of Munich (TUM) in Germany and AstraZeneca, among others, have identified a new type of cell therapy with the potential to heal injuries to the heart after a heart attack. The preclinical study, published in the journal Nature Cell Biology, shows that so-called ventricular progenitor cells can stimulate the heart’s
