Disarming the neutrophils induced lethal lung response through PTP1B inhibitors which regulate CXCR4 signaling

The Takeaway Neutrophils are the body’s first line of defense against infection. But if too many attack for too long, they can damage the tissues they’re meant to protect. In the lungs, this damage can lead to acute respiratory distress syndrome, the leading cause of death due to COVID-19. CSHL researchers have found that using

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COVID-19 mutations accelerated by virus-fighting enzyme in human cells, according to new research

The findings by a team of USC researchers could help scientists predict new coronavirus variants and subvariants and give them a leg up on producing effective vaccines. Researchers have found the first experimental evidence explaining why the COVID-19 virus produces variants, such as delta and omicron, so quickly. The findings, published Sept. 13 in the journal Scientific Reports,

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At least 17 million people in the WHO European Region experienced long COVID in the first two years of the pandemic; millions may have to live with it for years to come

WHO/Europe urges countries to take post COVID-19 condition seriously by urgently investing in research, recovery, and rehabilitation New modelling conducted for WHO/Europe by the Institute for Health Metrics and Evaluation (IHME) at the University of Washington’s School of Medicine in the United States shows that in the first two years of the pandemic, at least

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NIH research : Bronchodilators don’t improve smoking-related respiratory symptoms in people without COPD

Researchers supported by the National Institutes of Health have found that dual bronchodilators – long-lasting inhalers that relax the airways and make it easier to breathe – do little to help people who do not have chronic obstructive pulmonary disease (COPD), but who do have respiratory symptoms and a history of smoking.    COPD, a lung disease

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How the gut may help to drive COVID-19

New findings from Flinders University have demonstrated a molecular link between COVID-19 and serotonin cells in the gut. The research could help provide further clues to what could be driving COVID-19 infection and disease severity and supports previous evidence that antidepressants, known as selective serotonin reuptake inhibitors (SSRIs), could reduce the severity of COVID symptoms.

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FDA Approves First Cell-Based Gene Therapy to Treat Adult and Pediatric Patients with Beta-thalassemia Who Require Regular Blood Transfusions

The U.S. Food and Drug Administration approved Zynteglo (betibeglogene autotemcel), the first cell-based gene therapy for the treatment of adult and pediatric patients with beta-thalassemia who require regular red blood cell transfusions.  “Today’s approval is an important advance in the treatment of beta-thalassemia, particularly in individuals who require ongoing red blood cell transfusions,” said Peter

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