NIH Researchers develop innovative model for risk assessment for hypertrophic cardiomyopathy

NIH-funded study incorporates new measures to better predict outcomes in chronic heart condition. Findings from a study supported in part by the National Institutes of Health (NIH) have identified a new model for predicting outcomes for hypertrophic cardiomyopathy (HCM), a heart condition with a prevalence of 1 in 500 people and a frequent cause of

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AI-powered electrocardiogram detects early signs of heart failure

UT South Western-led Kenya study suggests relatively inexpensive technology could reduce cardiac health disparities in developing countries Interpreting relatively inexpensive electrocardiograms (ECGs) with an artificial intelligence (AI) algorithm accurately screened patients for a key precursor of heart failure in Kenya, a study led by UT Southwestern Medical Center researchers shows. The results, published in JAMA Cardiology, suggest

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Hydraulic brain: Body motion linked to fluid movement in the brain and washing away cerebral waste

Abdominal contractions are tightly linked to gentle brain movements that help circulate cerebrospinal fluid, researchers find in mouse study The brain is more mechanically connected to the body than previously appreciated, scientists reported today (April 27) in Nature Neuroscience. Through a study using mice and simulations, the team found a potential biological mechanism underlying why exercise is

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Stem Cell Memory CAR T Cells Achieve Complete Remissions at Low Doses Without Chemotherapy Preconditioning

Stem-cell memory T (TSCM) cells are a rare subset of immune cells with the ability to self-renew, persist long term, and mount potent anti-tumor responses. These properties make them an attractive candidate for next-generation CAR T-cell therapies. However, their clinical potential has not previously been demonstrated in humans. An international team of researchers co-led by

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Blood stem cells evade immunity in aplastic anemia by similar genetic mutations arising independently

A genomic study of the largest pediatric and adult aplastic anemia cohort genetically profiled to date, finds that protective mutations arise as independent events in different stem cells years before diagnosis. Aplastic anemia is a rare, life-threatening blood disorder where patients are unable to make enough blood cells due to the immune system’s attack on

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New OBSCORE tool helps to identify people at highest risk of obesity-related diseases

A simple tool, developed by researchers at Queen Mary University of London and the Berlin Institute of Health at Charité, could help identify which people living with obesity or overweight are most likely to develop serious obesity-related conditions such as type 2 diabetes and heart disease. The study, published in Nature Medicine, shows that future risk

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Umbilical cord blood transplant with pooled stem cell product shows 96% survival and no graft-versus-host-disease in leukemia patients

A phase 2 study published in the Journal of Clinical Oncology shows that a stem cell product called dilanubicel safely enabled umbilical cord blood transplants in 28 patients A new way of using umbilical cord blood for treating blood diseases could make the treatment more accessible to patients who need a stem cell transplant. A

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2026 American Heart Association Dietary Guidance to Improve Cardiovascular Health

Following 9 key steps for a lifetime of eating well can support heart health More than half of adults and about 60% of children in the U.S. have unhealthy diets, which can contribute to higher rates of health factors such as high blood pressure and obesity, and lead directly to poor health outcomes including deaths from cardiovascular disease and other

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