Stanford Medicine study shows why mRNA-based COVID-19 vaccines can cause myocarditis

A new study implicates a pair of substances secreted by immune cells in inducing myocarditis among mRNA-based COVID-19 vaccine recipients — and proposes a strategy to mitigate this effect. tanford Medicine investigators have unearthed the biological process by which mRNA-based vaccines for COVID-19 can cause heart damage in some young men and adolescents — and

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Short and long-term risks of vascular and inflammatory diseases following first COVID-19 diagnosis and vaccination in children and young people.

A new study shows children and young people face long-lasting and higher risks of rare heart and inflammatory complications after COVID-19 infection, compared to before or without an infection. Meanwhile, the COVID-19 vaccination was only linked to a short-term higher risk of myocarditis and pericarditis. The study is the largest of its kind in this

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Critical step in COVID viral infection identified

Researchers at Texas Biomedical Research Institute and University of Chicago have uncovered a mechanism that SARS-CoV-2, the virus that causes COVID-19, uses to protect itself inside the body as it works to replicate and infect more cells. Without this protective mechanism, viral infection is dramatically reduced. The finding, published in Nature Communications, not only provides a

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Impact of COVID-19 pandemic on the incidence and prevalence of postural orthostatic tachycardia syndrome

After the COVID-19 pandemic, the incidence rate of postural orthostatic tachycardia syndrome increased significantly, according to new data published in the European Heart Journal – Quality of Care and Clinical Outcomes. “Postural orthostatic tachycardia syndrome (POTS) is a chronic condition characterized by an abnormal increase in heart rate upon standing, often accompanied by symptoms such as dizziness, lightheadedness, fatigue

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Cellular interactions help explain vascular complications due to COVID-19 virus infection

COVID-19 is a respiratory disease primarily affecting the lungs. However, the SARS-CoV-2 virus that causes COVID-19 surprised doctors and scientists by triggering an unusually large percentage of patients to experience vascular complications – issues related to blood flow, such as blood clots, heart attacks, and strokes. Whitehead Institute Founding Member Rudolf Jaenisch and colleagues wanted

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Johns Hopkins APL Modeling Tool Affirms Critical Role of Testing in Pandemic Response

A new study in The Lancet Public Health found that early COVID-19 test development and distribution saved millions of lives. The COVID-19 pandemic highlighted how crucial testing is for disease preparedness and response, and new research from the Johns Hopkins Applied Physics Laboratory (APL) and a team of collaborators underscores that principle. Published in the

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COVID-19 Linked to Long-Term Risk for Autoimmune, Autoinflammatory Disease

Long-term monitoring and management of patients is crucial after COVID-19, considering demographic factors, disease severity, and vaccination status, to mitigate these risks. In a population-based study published in JAMA Dermatology, researchers from the Republic of Korea investigated whether having a history of coronavirus disease 2019 (COVID-19) increased the long-term risk of autoimmune and autoinflammatory connective tissue disorders.

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