Researchers at Texas Biomedical Research Institute and University of Chicago have uncovered a mechanism that SARS-CoV-2, the virus that causes COVID-19, uses to protect itself inside the body as it works to replicate and infect more cells. Without this protective mechanism, viral infection is dramatically reduced. The finding, published in Nature Communications, not only provides a
The host protein fibrinogen has been found to interact with the N-terminal domain (NTD) of the spike protein in SARS-CoV-2 as an immune evasion strategy adopted by the virus to outsmart the NTD targeted neutralizing antibodies. The journey of the COVID-19 virus, which emerged in early 2019, has been nothing short of remarkable as it
After the COVID-19 pandemic, the incidence rate of postural orthostatic tachycardia syndrome increased significantly, according to new data published in the European Heart Journal – Quality of Care and Clinical Outcomes. “Postural orthostatic tachycardia syndrome (POTS) is a chronic condition characterized by an abnormal increase in heart rate upon standing, often accompanied by symptoms such as dizziness, lightheadedness, fatigue
COVID-19 is a respiratory disease primarily affecting the lungs. However, the SARS-CoV-2 virus that causes COVID-19 surprised doctors and scientists by triggering an unusually large percentage of patients to experience vascular complications – issues related to blood flow, such as blood clots, heart attacks, and strokes. Whitehead Institute Founding Member Rudolf Jaenisch and colleagues wanted
A new study in The Lancet Public Health found that early COVID-19 test development and distribution saved millions of lives. The COVID-19 pandemic highlighted how crucial testing is for disease preparedness and response, and new research from the Johns Hopkins Applied Physics Laboratory (APL) and a team of collaborators underscores that principle. Published in the
Long-term monitoring and management of patients is crucial after COVID-19, considering demographic factors, disease severity, and vaccination status, to mitigate these risks. In a population-based study published in JAMA Dermatology, researchers from the Republic of Korea investigated whether having a history of coronavirus disease 2019 (COVID-19) increased the long-term risk of autoimmune and autoinflammatory connective tissue disorders.
A study today in JAMA suggests that hospitalized patients—primarily previously healthy young men—have considerably fewer cardiovascular sequelae by 18 months if they develop myocarditis after COVID-19 mRNA vaccination than after COVID-19 infection. French researchers mined data from the French National Health Data System on all 4,635 residents aged 12 to 49 years hospitalized for myocarditis, or inflammation of the heart
Risk of new diabetes diagnosis was higher compared with non-COVID respiratory infections Children and teens had an increased risk of being diagnosed with type 2 diabetes after COVID-19 infection, a retrospective cohort study of over 600,000 youth suggested. Adolescents 10 to 19 years old had a 55% higher risk for a new diagnosis of type
Authors say findings support considering convalescent plasma deployment for future infectious diseases emergencies A new study led by researchers at Johns Hopkins Bloomberg School of Public Health estimates that thousands of lives could have been saved during the first year of the COVID-19 pandemic if convalescent plasma had been used more broadly, particularly in outpatients
Research analysis reveals risk of cardiac events also varied by blood type and stays elevated for years after diagnosis A history of COVID-19 can double the risk of heart attack, stroke or death according to new research led by Cleveland Clinic and the University of Southern California. The study found that people with any type of COVID-19
