Severe Covid-19: new anti-C5a antibody approved by FDA

A new antibody drug by pharmaceutical company inflaRx received FDA emergency use authorization to treat critically ill Covid-19 patients. One of the greatest hurdles for monoclonal antibody development during the Covid-19 pandemic is the ongoing mutation of the SARS-CoV-2 virus. Most antibodies introduced throughout the pandemic targeted the virus spike protein, which mutates significantly with every emerging

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How COVID-19 Can Impact the Heart

Hearts from mice infected with COVID-19 have an increased percentage of fibrosis and dilation of the fibers—a common indicator of early cardiomyopathy in mice. Image courtesy of Andrew Marks. Scientists find that COVID-19 infection can cause changes in calcium channels that can affect how the heart beats, it can also trigger inflammation and oxidative stress

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McMaster University-led trial reduces COVID-19 hospitalization risk with single injection of pegylated interferon lambda

A team led by McMaster University researchers Gilmar Reis and Edward Mills has discovered that a single injection of pegylated interferon lambda can successfully treat COVID-19 in people early in the disease. A team led by McMaster University researchers Gilmar Reis and Edward Mills has discovered that a single injection of pegylated interferon lambda (lambda)

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Host-Cell Factors Involved in COVID-19 Infections May Augur Improved Treatments

By addressing molecules governing how host cells respond to the SARS-CoV-2 virus, researchers hope they’ve found a new therapeutic target less vulnerable to potential drug resistance and emerging variants of concern Researchers at University of California San Diego and UC Riverside have further elucidated the molecular pathway used by the SARS-CoV-2 virus to infect human

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Report highlights cost of misinformation to healthcare services during COVID-19 pandemic

A new report has highlighted the consequences of misinformation, including loss of trust in public institutions, delayed action on pressing issues such as climate change, and the financial toll on healthcare services during the COVID-19 pandemic. The ‘Fault Lines’ report involved a panel of international experts, including leading cognitive scientist Professor Stephan Lewandowsky, from the University of

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Myocardial Involvement After Hospitalization for COVID-19 Complicated by Troponin Elevation: A Prospective, Multicenter, Observational Study

People hospitalized with COVID-19 may have an increased risk for heart damage, but not so much the type of inflammation previous research suggested, according to a new study. Early in the pandemic, several studies suggested many COVID-19 survivors experienced heart damage even if they didn’t have underlying heart disease and weren’t sick enough to be hospitalized. The

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90% reduction in COVID-19 deaths after booster dose: Hong Kong study

A booster (third) dose of a SARS-CoV-2 vaccine was associated with a 90% reduction in death in people with multiple health conditions compared to 2 doses, according to a new study from Hong Kong published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221068. “We found a substantially reduced risk of COVID-19–related death in adults with multimorbidity who received a

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COVID-19 patients retain elevated risk of death for at least 18 months after infection

 COVID-19 is associated with higher risks of cardiovascular disease and death in the short- and long-term, according to a study in nearly 160,000 participants published today in Cardiovascular Research, a journal of the European Society of Cardiology (ESC). Compared to uninfected individuals, the likelihood of COVID-19 patients dying was up to 81 times higher in

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