Archives July 2019

How digital health tools can help transform healthcare

By J Doyle and S Reimer A coming wave of digital health tools has the potential to transform how and where healthcare is provided. Using information from a patient’s medical record—including lab results, provider notes and images, such as CT scans—along with genomic data, prior insurance claims and environmental information, machine learning algorithms can substantially

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Mesenchymal Stem Cells for Perianal Crohn’s Disease

Perianal fistulizing Crohn’s disease (PFCD) is associated with significant morbidity and might negatively impact the quality of life of CD patients. In the last two decades, the management of PFCD has evolved in terms of the multidisciplinary approach involving gastroenterologists and colorectal surgeons. However, the highest fistula healing rates, even combining surgical and anti-TNF agents,

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The Digital Doctor: The Next Big Leap in Healthcare

Technology has become increasingly important to the healthcare industry. Video chat allows patients to see a doctor in the comfort of their home; apps and wearable technology have revolutionized how health can be monitored.   However, as technology’s role becomes clearer, so does the uncertainty around its regulations, efficacy, and access.   Tabassum Salam, MD, American College of Physician

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CAR T cell therapies in pediatric oncology: access and future development by distributed academic cell manufacturing

Novel automation technologies enable the decentralized manufacturing of highly standardized CAR-T cell products in academic GMP facilities experienced with the production of patient-individual cell therapies. Dr Janet Rossig discusses the benefits of academic cell manufacturing, namely supporting the informed dissemination of CAR-T cell therapy to patients who benefit from this modality. She argues that this

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Stem cell therapy furthers research for infants with hypoplastic left heart syndrome

A phase I clinical trial is the first research monitored by the Food and Drug Administration that demonstrates the potential of regenerative therapy for hypoplastic left heart syndrome (HLHS) through collecting, processing and injecting an infant’s own stem cells directly into the heart at the time of surgery. A paper detailing the clinical trial was published in The

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New Cause of Cell Aging Uncovered. New research from the USC Viterbi School of Engineering could be key to our understanding of how the aging process works.

New research from the USC Viterbi School of Engineering could be key to our understanding of how the aging process works. The findings potentially pave the way for better cancer treatments and revolutionary new drugs that could vastly improve human health in the twilight years. The work, from Assistant Professor of Chemical Engineering and Materials

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To become, or not to become… a neuron. Scientists find a factor that makes neural stem cells “deaf” to proliferative signals, turning them into neurons

Researchers led by Pierre Vanderhaeghen and Jérôme Bonnefont (VIB-KU Leuven and ULB), in collaboration with Stein Aerts (VIB KU Leuven) and François Guillemot (Crick Institute), have unraveled a new mechanism controlling the switch between growth and differentiation of neural stem cells during brain development. They discovered a specific factor that makes stem cells ‘deaf’ to proliferative signals,

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Some health websites are notoriously misleading: their reliability rated

Source STAT For millions of Americans, including health professionals, the resurgence of measles is a confounding and frightening development. How can a disease declared eliminated nearly two decades ago come back when it can be prevented with a vaccine proven to be safe and effective? But that’s not the reality for those getting their health information from

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