The U.S. Food and Drug Administration approved Itvisma (onasemnogene abeparvovec-brve) for the treatment of spinal muscular atrophy (SMA) in adult and pediatric patients 2 years of age and older with confirmed mutation in the survival motor neuron 1 (SMN1) gene. Itvisma is an adeno-associated virus (AAV) vector-based gene therapy. “Today’s approval shows the power of
A new study tracking the mental health of adults in the Gaza Strip suggests that psychological distress has tripled over the past five years, with a sharp increase following the conflict escalation in October 2023. The research, published in eClinicalMedicine, analyzed data from 677 people aged 40 and older who participated in three household surveys conducted
In a first-in-human phase 1/2a clinical trial, researchers used adult stem cells to improve vision in patients with age-related macular degeneration In the United States, age-related macular degeneration is a leading cause of irreversible vision loss in people who are 60 and older. It affects the central portion of the retina, called the macula. This
New research from Cambridge University suggests that improving diet and increasing physical activity levels may be more effective in preventing weight gain, especially harmful abdominal fat, than simply changing one of these behaviors. An analysis of changes in physical activity and diet quality among British adults found that while improvements in diet quality and increases
Mount Sinai study shows that traditional risk scores and symptoms such as chest pain should not be solely relied upon to prevent cardiovascular events Current cardiac screening tools used to prevent heart attacks fail to identify nearly half of the people who are actually at risk of having one, according to a new study led
Atrial fibrillation can develop silently, without any obvious symptoms, yet it poses a real health threat. This insidious condition affects tens of millions of people globally, with the number of diagnosed cases steadily increasing. Early detection of irregular heartbeat could prevent many complications, but traditional methods require regular checkups with a specialist. However, an unexpected
Texas A&M researchers have developed a patch to repair damaged tissue and promote the growth of new cells. A new patch developed by Texas A&M University researcher Dr. Ke Huang may offer a way to help the heart heal after a heart attack. The patch uses a unique microneedle system to deliver a therapeutic molecule directly to
In a surprising discovery, a ‘sticky molecule’ that occurs naturally in our blood vessels could be both a culprit behind blood clots and organ failure during COVID and long COVID and the key to new treatments to counter COVID-related viruses. Researchers say the molecule, called P-selectin, could turn the tide to develop a new generation
New approach could be applied to other complex, genetically influenced diseases like cancer and Parkinson’s In a new Northwestern Medicine study, scientists have developed a more precise genetic risk score to determine whether a person is likely to develop arrhythmia, an irregular heartbeat that can lead to serious conditions such as atrial fibrillation (AFib) or
Research Highlights: Among people with a previous heart attack or stroke, or who are at high risk for one, a daily oral medication may offer an effective alternative to injections of PCSK9 inhibitors to lower low-density lipoprotein (LDL or “bad” cholesterol), according to a preliminary late-breaking science presentation today at the American Heart Association’s Scientific Sessions 2025. The meeting, Nov.
