Researchers at Chalmers University of Technology, in Sweden, shed new light on the remaining risk of heart disease, even after the known risk factor of ‘bad’ cholesterol is brought down to a healthy level. In a new study, key biological pathways – and an understanding of how the body is affected – were identified for
Exercise should be prescribed as a foundational component of cardiovascular disease (CVD) prevention and treatment, according to a new American College of Cardiology scientific statement published in JACC. The statement emphasizes that the greatest reduction in cardiovascular risk occurs when sedentary individuals become even modestly more active, and the best exercise prescription is one that
Experts from EBMT, ISCT and JACIE, with representatives from EULAR and ECTRIMS, have published updated recommendations supporting careful patient selection, multidisciplinary care and long-term follow-up as CAR T-cell therapy expands beyond cancer. An international multidisciplinary group of 31 experts has updated consensus recommendations for using chimeric antigen receptor (CAR) T-cell therapy in people with severe,
Five years after a landmark result in a single patient, new findings from the first treated cohort show that optogenetic vision restoration can work beyond an individual case. Scientists have taken another important step toward restoring vision in people with certain inherited forms of blindness. In a study published in the New England Journal of
Researchers identify additional gene controlling production of fetal hemoglobin Harvard Medical School researchers at Boston Children’s Hospital and Dana-Farber Cancer Institute have identified a new pathway that regulates the production of fetal hemoglobin, a form of hemoglobin that normally gets replaced soon after birth by adult hemoglobin. Two FDA-approved gene therapies reactivate the production of
The research, presented in a Hot Line session at the European Society of Cardiology Congress in Munich and published simultaneously in The New England Journal of Medicine, proposes a paradigm shift towards prevention based on early detection through vascular imaging Atherosclerosis, the process underlying most cardiovascular diseases, begins long before the first symptoms appear. An international
Retatrutide treatment results in substantial weight loss among patients with obesity, as well as reduced pain in patients with knee osteoarthritis and reduced apnea-hypopnea events in patients with obstructive sleep apnea, according to the TRIUMPH-1 study.1 Earlier phase 2 trials including patients with obesity have indicated that once-weekly subcutaneous retatrutide resulted in substantial weight reductions
