Archives October 2019

FDA approves new breakthrough therapy for cystic fibrosis

Treatment approved for approximately 90% of patients with cystic fibrosis, many of whom had no approved therapeutic options Source FDA The U.S. Food and Drug Administration today approved Trikafta (elexacaftor/ivacaftor/tezacaftor), the first triple combination therapy available to treat patients with the most common cystic fibrosis mutation. Trikafta is approved for patients 12 years and older

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Assessment of Accuracy of an Artificial Intelligence Algorithm to Detect Melanoma in Images of Skin Lesions

Source JAMA Network Open IMPORTANCE A high proportion of suspicious pigmented skin lesions referred for investigation are benign. Techniques to improve the accuracy of melanoma diagnoses throughout the patient pathway are needed to reduce the pressure on secondary care and pathology services. OBJECTIVE To determine the accuracy of an artificial intelligence algorithm in identifying melanoma

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New Gene Therapy Approach Reduces Cost and Improves Efficiency

A more efficient approach to gene therapy that could lower costs and improve patient outcomes has recently been developed by a team from Scripps Research. This work, published on October 17 in the journal Blood, offers a potential alternative to the standard process of delivering gene therapy, which is expensive, time-consuming, and requires many steps to administer healthy

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Stem Cell Therapy for ALS

Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease and Lou Gehrig’s disease, is a rare condition characterized by the degeneration of nerve cells that control voluntary muscles. The disease leads to gradually worsening symptoms that include muscle weakness, twitching, and stiffness. As more of these nerve cells, or motor neurons, are lost, muscles decrease in size

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FDA’s Framework for Regulating Regenerative Medicine Will Improve Oversight. New report released by The Pew

Further action needed to facilitate development of safe, effective treatments Source The Pew Over the last two decades, cell therapies (which involve the transplantation of whole cells into a patient), gene therapies (which use genetic material to manipulate a patient’s cells), and other medical treatments intended to repair or replace damaged, diseased, or dysfunctional cells,

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Science writers discuss public perceptions, misconceptions about science

Scientific research follows processes to validate, refute prior evidence Source The Badger Herald A panel of science writers and experts discussed the importance of understanding uncertainty in the scientific process at the Discovery Building Wednesday night.  The University of Wisconsin’s 2019 Science Writer in Residence Christie Aschwanden’s scientific journalism has appeared in FiveThirtyEight, the Washington Post,

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Panel Finds Exercise May Lower Cancer Risk, Improve Outcomes

Source NIH Director’s Blog Exercise can work wonders for your health, including strengthening muscles and bones, and boosting metabolism, mood, and memory skills. Now comes word that staying active may also help to lower your odds of developing cancer.  After reviewing the scientific evidence, a panel of experts recently concluded that physical activity is associated with reduced

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