Archives: 2022-09-29

PIER MARIA FORNASARI
2022-09-29

 Short documentary video from the New England Journal of Medicine on Sickle Cell Disease and Gene Therapy from Patient and Physician Perspectives

In this short documentary video from the New England Journal of Medicine, patients and physicians partner both to highlight the experience of living with sickle cell disease and to discuss the pathophysiology of the disease and new treatment strategies, including gene therapy. Patients share their own stories of interactions with the health care system and explore

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No Comments InGENE THERAPY RARE DISEASES
PIER MARIA FORNASARI
2022-09-27

Coffee drinking is associated with increased longevity: a study of European Society of Cardiology finds.

Drinking two to three cups of coffee a day is linked with a longer lifespan and lower risk of cardiovascular disease compared with avoiding coffee, according to research published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology. The findings applied to ground, instant and decaffeinated varieties. “In this large, observational

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No Comments InWELLNESS
PIER MARIA FORNASARI
2022-09-27

Scientists identify WASH protein complex as a gatekeeper of neutrophil-driven inflammation

A team led by Scripps Research scientists has uncovered key details of an immune-cell process that frequently underlies excessive inflammation in the body. The findings could lead to new ways of preventing and/or treating inflammation-related conditions such as sepsis, arthritis, and coronary artery disease. In the study, published September 21, 2022 in Nature Communications, the researchers

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No Comments InRESEARCH
PIER MARIA FORNASARI
2022-09-27

Calibr, a Division of Scripps Research, reports promising results from first-in-human clinical trial of switchable CAR-T (CLBR001 + SWI019), a next-generation universal CAR-T platform designed to enhance the versatility and safety of cell therapies

In preliminary results from a Phase I study of CLBR001 + SWI019 for patients with B cell malignancies: 7 of 9 patients responded and 6 of 9 had a complete response (78% ORR, 67% CR) CLBR001 cells engrafted at higher levels than approved CAR-T cell products without causing an increase in the incidence of CRS

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PIER MARIA FORNASARI
2022-09-27

Ecological niche modelling analyses highlight a risk of expansion of Lassa virus towards Central and East Africa potentially leading to a drastic increase in the number of people exposed.

In the study, which appeared on September 27 in Nature Communications, scientists analyzed decades of environmental data associated with Lassa virus outbreaks, revealing temperature, rainfall and the presence of pastureland areas as key factors contributing to viral transmission. The researchers projected that areas hospitable to Lassa virus spread may extend from West Africa into Central and

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No Comments InWELLNESS
PIER MARIA FORNASARI
2022-09-27

New study of Case Western Reserve University: Risk factor for developing Alzheimer’s disease increases by 50-80% in older adults who caught COVID-19

Older people who were infected with COVID-19 show a substantially higher risk—as much as 50% to 80% higher than a control group—of developing Alzheimer’s disease within a year, according to a study of more than 6 million patients 65 and older. In a study published in the Journal of Alzheimer’s Disease, researchers report that people 65

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No Comments InCovid-19
PIER MARIA FORNASARI
2022-09-25

New University of California Irvine-led report Illustrates potential of precision genome editing in treating inherited retinal diseases

Improvements in technology and delivery techniques could revolutionize treatment of genetic disorders of vision In a new paper, University of California, Irvine researchers explain how precision genome editing agents have enabled precise gene correction and disease rescue in inherited retinal diseases (IRDs). The study, titled, “Precision genome editing in the eye,” was published this week

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No Comments InGENE EDITING