Archives April 2020

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

The novel coronavirus SARS-CoV-2, the causative agent of COVID-19 respiratorydisease, has infected over 2.3 million people, killed over 160,000, and causedworldwide social and economic disruption.There are currently no antiviral drugs with proven clinical efficacy, nor are there vaccines for its prevention, and these efforts are hampered by limited knowledge of the molecular details of SARS-CoV-2

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COVID-19: Launched a new National Convalescent Plasma Website for Healthcare providers and Patients

Treatment of COVID-19 is urgent. As part of the next step to advance the use of convalescent plasma for the treatment of COVID-19 infection, the National Convalescent Plasma Project has launched a website for health care providers, patients who have recovered from COVID-19 infection and want to donate plasma and those considering the treatment.  On March 25,

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In Covid-19 recovered patients, South Korean KCDC experts found false positives, not reinfections

South Korea’s infectious disease experts said Thursday that dead virus fragments were the likely cause of over 260 people here testing positive again for the novel coronavirus days and even weeks after marking full recoveries. Oh Myoung-don, who leads the central clinical committee for emerging disease control, said the committee members found little reason to

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Santhera and Cold Spring Harbor Laboratory to Investigate Lonodelestat in COVID-19-related Acute Respiratory Distress Syndrome (ARDS)

Santhera Pharmaceuticals (SIX: SANN) has entered into a collaboration agreement with Cold Spring Harbor Laboratory (CSHL) to investigate the potential of lonodelestat (POL6014), a potent inhibitor of human neutrophil elastase (hNE), as a therapeutic intervention for COVID-19-related acute respiratory distress syndrome (ARDS). Researchers at CSHL are part of a recently formed consortium of international non-clinical and

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New research finds a connection between NETs and a more severe disease course of Covid-19

New research finds a connection between destructive white blood cells and a more severe disease course in patients with COVID-19. Source University of Michigan “We found that patients with COVID-19 infection have higher blood levels of neutrophil extracellular traps, also called NETs, which are a product of an inflammatory type of neutrophil cell death called NETosis,” says first

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Fighting the Covid-19 ‘infodemic’: conspiration theories and fake news

Disinformation and conspiracy theories surrounding the global coronavirus pandemic have flooded the internet – often with an additional nudge from world leaders and celebrities – presenting a challenge for health authorities, social media platforms, journalists, fact-checkers and concerned citizens worldwide. US health officials scrambled this week to put out a fire started by President Donald Trump when he suggested in his Thursday press briefing that injecting disinfectant

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FDA OKs ADHD Video Game Therapy for Emergency Release During the Pandemic

In response to U.S. stay-at-home orders, the FDA has cleared the way for the emergency release of several validated digital therapeutics including Endeavor™ (AKL-TO1), a digital attention treatment from Akili Interactive. Endeavor™, a computer game experience that aims to improve attention function in children ages 8-12 with primarily inattentive or combined-type ADHD, is now available

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For WHO “No evidence” that recovered COVID-19 patients cannot be reinfected, warning governments against issuing “immunity passports”

The World Health Organization (WHO) said that there was currently “no evidence” that people who have recovered from COVID-19 and have antibodies are protected from a second coronavirus infection. In a scientific brief, the United Nations agency warned governments against issuing “immunity passports” or “risk-free certificates” to people who have been infected as their accuracy

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