Penn study reveals an easier, more scalable way to make a powerful immunotherapy An experimental immunotherapy can temporarily reprogram patients’ immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of Medicine
The past year of the Covid-19 pandemic has been driven by variants, now designated as Alpha, Beta, Gamma, Delta, and now Omicron. It is natural to wonder what will be next. Scientists and epidemiologists around the world are alert to the possibility that yet another dangerous variant may arise. This is the context to understand
Today, a group of eminent physicians and scientists with global standing have acted decisively and in unison presenting the world with what it badly needs, whether it knows it or not: a comprehensive, cohesive plan which lays out the steps to reverse the course of Covid-19. Presented today as three linked “Viewpoints” in one of the world’s
Efforts to contain the spread of SARS-CoV-2 may benefit from a new analytical tool developed by a team led by biologists at Boston College, who report their computer simulation of molecular interactions can predict mutations of the virus and help develop insights into future variants of concern before they emerge. “We computationally predict what mutations
Anew study raises significant doubts about whether at-home rapid antigen tests can detect the Omicron variant before infected people can transmit the virus to others. The study looks at 30 people from settings including Broadway theaters and offices in New York and San Francisco where some workers were not only being tested daily but were, because
A new paper published on JAMA Pediatrics by researchers of Columbia University Irving Medical Center analyses a ssociations between in utero exposure to maternal SARS-CoV-2 infection and neurodevelopment which are speculated, but currently unknown. To examine the associations between maternal SARS-CoV-2 infection during pregnancy, being born during the COVID-19 pandemic regardless of maternal SARS-CoV-2 status,
The first comprehensive analysis of its kind examines hospital inpatient costs and length of stay. A new study published in Advances in Therapy provides the first comprehensive analysis of the hospitalization costs for COVID-19 patients, factors associated with costs and length of stay, and the monthly trends of costs and length of stay from April to December
In South Africa, the pattern of patients hospitalized with COVID-19 early in the fourth wave showed fewer hospitalizations and reduced severity of illness compared with earlier waves, according to a research letter published online Dec. 30 in the Journal of the American Medical Association. Caroline Maslo, M.D., Ph.D., from Netcare Ltd. South Africa in Johannesburg, and
Researchers at Baylor College of Medicine have investigated the effect of infection with COVID-19 on the levels of oxidative stress, oxidant damage and glutathione, the most abundant physiological antioxidant. Compared to healthy age-matched individuals whose samples were taken before the pandemic started in 2019, patients hospitalized with COVID-19 had significantly increased levels of oxidative stress and
Diffuse large B-cell lymphoma. Photograph by CoRus13, distributed under a CC BY-SA 4.0 license Aggressive and relatively common lymphomas called diffuse large B cell lymphomas (DLBCLs) have a critical metabolic vulnerability that can be exploited to trick these cancers into starving themselves, according to a study from researchers at Weill Cornell Medicine and Cornell’s Ithaca campus.
