Covid-19 – Page 50 – REGENHEALTHSOLUTIONS (RHS)

PIER MARIA FORNASARI
2020-12-29

NIH observational study of coronavirus infection and multisystem inflammatory syndrome in children begins

An observational study has launched to evaluate the short- and long-term health outcomes of SARS-CoV-2 infection in children, including multisystem inflammatory syndrome in children (MIS-C), and to characterize the immunologic pathways associated with different disease presentations and outcomes. SARS-CoV-2 is the virus that causes COVID-19. The study, called the Pediatric Research Immune Network on SARS-CoV-2

No Comments InCovid-19

PIER MARIA FORNASARI
2020-12-29

One Year Later, How Does COVID-19 Affect Children?

Children get sick less often than adults due to Covid-19, but children are at risk. This is the key insight from a paper in the Journal of American Medical Association (JAMA), a peer-reviewed medical journal, as the year draws to an end. The paper summarizes the current understanding of how children are affected by Covid-19. So far

No Comments InCovid-19

PIER MARIA FORNASARI
2020-12-28

SARS-CoV-2 vaccine update

Vaccines typically require years of research and testing before reaching the clinic, but in 2020, scientists embarked on a race to produce safe and effective coronavirus vaccines in record time. Researchers are currently testing 64 vaccines in clinical trials on humans, and 19 have reached the final stages of testing. At least 85 preclinical vaccines are under active

No Comments InCovid-19

PIER MARIA FORNASARI
2020-12-27

D614G mutation alters SARS-CoV-2 spike conformation and enhances protease cleavage at the S1/S2 junction

The SARS-CoV-2 spike (S) protein is the target of vaccine design efforts to end the COVID-19 pandemic. Despite a low mutation rate, isolates with the D614G substitution in the S protein appeared early during the pandemic, and are now the dominant form worldwide. In this paper are explored spike conformational changes and the effects of

No Comments InCovid-19

PIER MARIA FORNASARI
2020-12-27

Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19

The SARS-CoV-2 pandemic poses an unprecedented public health crisis. Evidence suggests that SARS-CoV-2 infection causes dysregulation of the immune system. However, the unique signature of early immune responses remains elusive. In this paper the transcriptome of rhesus macaques and mice infected with SARS-CoV-2 was characterized. Alarmin S100A8 was robustly induced in SARS-CoV-2 infected animal models

No Comments InCovid-19

PIER MARIA FORNASARI
2020-12-20

Preliminary genomic characterisation of an emergent SARS-CoV-2 lineage in the UK defined by a novel set of spike mutations

Recently a distinct phylogenetic cluster (named lineage B.1.1.7) was detected within the COG-UK surveillance dataset. This cluster has been growing rapidly over the past 4 weeks and since been observed in other UK locations, indicating further spread. Several aspects of this cluster are noteworthy for epidemiological and biological reasons and we report preliminary findings below.

No Comments InCovid-19

PIER MARIA FORNASARI
2020-12-18

Which appropriate SARS-CoV-2 test to select.

There’s a growing variety and availability of tests related to SARS-CoV-2. All types of tests can help healthcare providers make more accurate diagnosis, support better management of individual patients and provide better guidance to manage population risk. Active infection is detected with RT-PCR tests detect the presence of SARS-CoV-2 based on its genetic make up (RNA). These tests

No Comments InCovid-19

PIER MARIA FORNASARI
2020-12-18

By October 2020 COVID-19 had become the third leading cause of death in US for persons aged 45 through 84 years and the second for those aged 85 years or older.

Adults 45 years or older were more likely to die from COVID-19 during those months than from chronic lower respiratory disease, transport accidents (eg, motor vehicle fatalities), drug overdoses, suicide, or homicide. In contrast, for individuals younger than age 45 years, other causes of death, such as drug overdoses, suicide, transport accidents, cancer, and homicide

No Comments InCovid-19

PIER MARIA FORNASARI
2020-12-15

Research Could Offer Novel Way to Restore Lung Function to COVID-19 Patients

Targeting endothelial cells –cells that comprise the blood vessel wall which regulate oxygen exchange between airways and the bloodstream– may be a novel approach restoring normal lung function to Covid-19 patients with serious lung disease. This hypothesis stems from a study by researchers in the Department of Microbiology and Immunology in the Renaissance School of

No Comments InCovid-19

PIER MARIA FORNASARI
2020-12-15

Covid-19 fighting: New Online Resources

There are lots of useful online resources to learn about COVID-19 and some of the clinical studies taking place across the country. What’s been missing is a one-stop online information portal that pulls together the most current information for people of all groups, races, ethnicities, and backgrounds who want to get involved in fighting the

No Comments InCovid-19

REGENERATIVE AND PERSONALISED MEDICINE

DIGITAL HEALTHCARE

Category Covid-19

NIH observational study of coronavirus infection and multisystem inflammatory syndrome in children begins

One Year Later, How Does COVID-19 Affect Children?

SARS-CoV-2 vaccine update

D614G mutation alters SARS-CoV-2 spike conformation and enhances protease cleavage at the S1/S2 junction

Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19

Preliminary genomic characterisation of an emergent SARS-CoV-2 lineage in the UK defined by a novel set of spike mutations

Which appropriate SARS-CoV-2 test to select.

By October 2020 COVID-19 had become the third leading cause of death in US for persons aged 45 through 84 years and the second for those aged 85 years or older.

Research Could Offer Novel Way to Restore Lung Function to COVID-19 Patients

Covid-19 fighting: New Online Resources