REGENERATIVE MEDICINE – Page 49 – REGENHEALTHSOLUTIONS (RHS)

PIER MARIA FORNASARI
2019-08-17

New Frontiers of Corneal Gene Therapy

Source https://www.liebertpub.com/doi/pdf/10.1089/hum.2019.026#utm_source=ETOC&utm_medium=email&utm_campaign=hum Corneal diseases are among the most prevalent causes of blindness worldwide. The transparency and clarity of the cornea are guaranteed by a delicate physiological, anatomic, and functional balance. For this reason, all the disorders, including those of genetic origin, that compromise this state of harmony can lead to opacity and eventually vision loss.

No Comments InGENE THERAPY RARE DISEASES

PIER MARIA FORNASARI
2019-08-16

Enhancing CAR T-cell therapy through cellular imaging and radiotherapy.

Source The Lancet. Oncology, ISSN: 1474-5488, Vol: 20, Issue: 8, Page: e443-e451 Chimeric antigen receptor (CAR) T-cell therapy is one of the most remarkable advances in cancer therapy in the last several decades. More than 300 adoptive T-cell therapy trials are ongoing, which is a testament to the early success and hope engendered by this

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PIER MARIA FORNASARI
2019-08-16

Social value decreases with delay of CAR-T cell therapy delivery

New research has observed that the benefits of CAR-T cell immunotherapies – for the treatment of diseases such as pediatric acute lymphoblastic leukemia and diffuse large B-cell lymphoma – may be offset by their delayed delivery to patients. The social value of a therapy balances manufacturer costs and profits versus a patient’s improvement in quality-adjusted

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PIER MARIA FORNASARI
2019-08-16

The “All of Us” Research Program : Progress report after 1 year

The vision is ambitious : Enroll 1 million people in the NIH’s All of Us Research program, whose goal is to make personalized medicine a reality for everyone. That means ensuring that more than half of participants come from communities historically underrepresented in biomedical research. A year after its launch, 230,000 people have joined, 80% of

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PIER MARIA FORNASARI
2019-08-16

Relaxing of regulations for regenerative medicines has cascading effect internationally

Countries that relax regulations for regenerative medicines could be causing a downward spiral in international standards, according to new research published today. Researchers warn that if just one country decides to relax regulations in the field, a heightened sense of competition can spur others to do the same. It’s unclear whether this deregulation best serves

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PIER MARIA FORNASARI
2019-08-15

New nanotechnology could aid stem cell transplantation research

Nanotechnology developed at Rutgers University-New Brunswick could boost research on stem cell transplantation, which may help people with Alzheimer’s disease, Parkinson’s disease, other neurodegenerative diseases and central nervous system injuries. The nanotechnology platform, which uses special tiny rods for sensing, allows researchers to confirm the identity of human stem cell fates and their biomarkers, or

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PIER MARIA FORNASARI
2019-08-15

PTPσ inhibitors promote hematopoietic stem cell regeneration

Receptor type protein tyrosine phosphatase-sigma (PTPσ) is primarily expressed by adult neurons and regulates neural regeneration. Researchers at UCLA recently discovered that PTPσ is also expressed by hematopoietic stem cells (HSCs) and describe small molecule inhibitors of PTPσ that promote HSC regeneration in vivo. Systemic administration of the PTPσ inhibitor, DJ001, or its analog, to

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PIER MARIA FORNASARI
2019-08-15

Novartis violated FDA’s sacred principle: In God we trust, all others must bring data. Robert Califf opinion

Source STAT A common saying at the Food and Drug Administration is: “In God we trust, all others must bring data.” The independent evaluation of science is an essential element of the FDA’s dual role of protecting the public health and promoting innovation to bring new therapies into practice. In fact, with certain exceptions, the

No Comments InGENE THERAPY RARE DISEASES

PIER MARIA FORNASARI
2019-08-15

Cambridge scientists reverse aging process in rat brain stem cells

New research reveals how increasing brain stiffness as we age causes brain stem cell dysfunction, and demonstrates new ways to reverse older stem cells to a younger, healthier state. New research, published today in Nature, reveals how increasing brain stiffness as we age causes brain stem cell dysfunction, and demonstrates new ways to reverse older stem

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PIER MARIA FORNASARI
2019-08-15

Immune-Activating Gene Therapy for Gliobastoma

The results of an early trial in 31 brain cancer patients finds immune activity boosted in the tumor, and possibly longer survival. An inducible, tumor-localized gene therapy has been tested for the first time in glioblastoma patients. The two-part approach, which involves receiving an injection of an immune-activator gene into the brain tumor site and

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REGENERATIVE AND PERSONALISED MEDICINE

DIGITAL HEALTHCARE

Category REGENERATIVE MEDICINE

New Frontiers of Corneal Gene Therapy

Enhancing CAR T-cell therapy through cellular imaging and radiotherapy.

The “All of Us” Research Program : Progress report after 1 year

Relaxing of regulations for regenerative medicines has cascading effect internationally

New nanotechnology could aid stem cell transplantation research

PTPσ inhibitors promote hematopoietic stem cell regeneration

Novartis violated FDA’s sacred principle: In God we trust, all others must bring data. Robert Califf opinion

Cambridge scientists reverse aging process in rat brain stem cells

Immune-Activating Gene Therapy for Gliobastoma