People with mild to moderate COVID-19 can shed viral RNA in their feces months after initial infection, Stanford researchers find. Those who do often have nausea, vomiting and abdominal pain. If you’re relying on nasal or throat-based tests to give you a clean bill of health after a COVID-19 infection, you might be swabbing the
Fifth generation polyrotaxane (PRX) carriers can effectively deliver CRISPR-Cas9 ribonucleoproteins (RNPs) The PRX carrier can cross the cell membrane, avoid endosomal action, and release Cas9 RNP for entry into the nucleusImage courtesy: Kumamoto University, The carriers, aminated polyrotaxanes, can flexibly and reversibly bind with Cas9 ribonucleoprotein and protect it from intracellular endosomal degradation CRISPR-Cas9 is
People with Long-COVID appear to be at higher risk of a blood clotting abnormality; risk may be four times greater for people with impaired exercise capacity (WASHINGTON, May 11, 2022) — According to a study published today in Blood Advances, people suffering from long COVID may face an increased risk of abnormal blood clotting. Investigators also
The neuropsychiatric sequelae are similar for severe COVID-19 infection and for other severe acute respiratory infections (SARI), according to a study published online May 11 in JAMA Psychiatry. Ashley Kieran Clift, M.B.B.S., from the University of Oxford in the United Kingdom, and colleagues quantified the risks of new-onset neuropsychiatric conditions and new neuropsychiatric medication prescriptions after discharge from
Certain genetic conditions in people significantly influence their immune response against the SARS-CoV-2 virus and can influence the severity of the COVID-19 disease. A research group led by MedUni Vienna was able to show that certain genetic variants of the CD16a antibody receptor are associated with the risk of severe COVID-19. Around 15 percent of
Two years after infection with COVID-19, half of patients who were admitted to hospitals still have at least one symptom, according to the longest follow-up study to date, published in The Lancet Respiratory Medicine. The study followed 1,192 participants in China infected with SARS-CoV-2 during the first phase of the pandemic in 2020. While physical and
Researchers from the Medway School of Pharmacy (a partnership between the universities of Kent and Greenwich) have helped isolate the Lloviu virus (LLOV) – a close relative of Ebola virus – for the first time, highlighting the need for future research to ensure pandemic preparedness. LLOV is part of the filovirus family – which includes the Ebola
The pig heart transplanted into an American patient earlier this year in a landmark operation carried a porcine virus that may have derailed the experiment and contributed to his death two months later, say transplant specialists. David Bennett Sr. was near death in January when he received a genetically edited pig heart in a pioneering between-species transplant
ANSM is publishing the final reports of the inspection conducted at the Institut hospitalo universitaire-Méditerranée Infection de Marseille (IHU) and at the Assistance Publique – Hôpitaux de Marseille (AP-HM), following reports in the context of our whistleblower system. The inspection reveals serious shortcomings and non-compliances with the regulations for research involving the human person (RIPH) , in particular
Overwhelming evidence shows that infection with severe acute respiratory syndrome (SARS-CoV-2) causes dysfunction of multiple organ systems, including the nervous system. Neurologic symptoms are frequently reported even in patients with mild illness and for some, these neurologic symptoms may persist as part of long-haul COVID. To describe the prevalence, associated risk factors and outcomes of
