Archives: 2019-10-29

Progressing toward successful gene-based approaches to inherited neurometabolic diseases

Researchers are making great strides toward de-veloping gene-based strategies to treat a variety of inherited neurometabolic diseases characterized by severe neurological involvement. A review of the approaches currently under preclinical or clinical investigation is published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. Click here to read the full-text article free on the Human

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Twitter reveals growing global public anxiety about Crispr gene-editing

The first ever analysis of all the tweets discussing Crispr gene-editing has revealed how the public feels about the technology. The findings suggest that over a six years public approval of gene-editing has cooled and that most people chatting about the technology are worried. Twitter offers researchers a vast amount of semi-structured data and provides direct access

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Immunotherapy Advances: 2019

The year 2019 has offered up many advances in immunotherapy. These advances shed light on such important aspects as biomarkers, better targeted therapies, chemotherapy outcomes, and resistance. Summarized herein are several high-profile conference presentations that highlight key advances in the field. The year has not quite come to an end yet, but as predicted by

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New KUBio box for viral vectors boosts gene therapy manufacturing

GE Healthcare Life Sciences is launching KUBio™ box, a fully-integrated, flexible, and adaptable biomanufacturing environment to accelerate the production of viral vector-based gene therapies. The latest addition to the KUBio modular bioprocessing portfolio, KUBio box is expected to speed gene therapies to market and contribute to increased capacity in the viral vector area. Gene therapies

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Stem cell-based therapies for Duchenne muscular dystrophy

Scientists of John Hopkins University School of Medicine summarize the current methods of human pluripotent stem cells (HPSCs) myogenic commitment/differentiation, and describe the current status of hPSC-derived myogenic cell transplantation. Muscular dystrophies are a group of genetic muscle disorders that cause progressive muscle weakness and degeneration. Within this group, Duchenne muscular dystrophy (DMD) is the

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CARsgen Announces Investigational CAR-T Therapy CT053, after PRIME eligibility by EMA, Granted RMAT Designation by the U.S. FDA for R/R Multiple Myeloma

CARsgen Therapeutics Co. Ltd., a clinical-stage biopharmaceutical company today announced that the United States Food and Drug Administration (FDA) has granted Regenerative Medicine Advanced Therapy (RMAT) designation to its investigational CT053 CAR-T cell therapy. CT053 is a fully human anti-BCMA (B Cell Maturation Antigen) autologous chimeric antigen receptor (CAR) T Cell therapy for the treatment of

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CAN SOLAR TECHNOLOGY KILL CANCER CELLS?

The results, published in the current issue of Scientific Reports, showcase dramatic improvements in light-activated fluorescent dyes for disease diagnosis, image-guided surgery and site-specific tumor treatment. Scientific breakthroughs don’t always happen in labs. For Sophia and Richard Lunt, Michigan State University researchers, many of their breakthroughs happen during neighborhood walks. The married couple’s step-by-step approach

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How Certain Foods Affect Cognition, Seizures, and Cardiometabolic Disease

Food for Thought Food for Thought periodically reports on nutrition research aimed at improving health and well-being. Rebecca Voelker, MSJ JAMA. Published online October 24, 2019. doi:10.1001/jama.2019.16477 The science behind food’s effects on human health is discovering some tasty benefits.Berries and Grapes Linked With Memory Boost As the world’s elderly population races toward an estimated 2 billion by

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