Archives: 2021-05-08

New research reveals why some patients may test positive for COVID-19 long after recovery

In the early months of the COVID-19 pandemic, healthcare workers analyzing test results began noticing something strange: patients who had already recovered from COVID-19 would sometimes inexplicably test positive on a PCR test weeks or even months later.  Although people can catch COVID-19 for a second time, this did not appear to be the case

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Fully vaccinated healthcare workers in Israel were up to 30 times less likely to be infected

Pfizer and BioNTech’s coronavirus reduces the risk of getting sick from COVID-19 by five- to 30-fold for fully immunized people, two new studies show.  In one report, just 0.4 percent of healthcare workers in Israel who received both shots of the COVID-19 immunization later tested positive compared to 7.2 percent of unvaccinated employees. This means healthcare workers who

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Norwegian-Danish registry study with findings on venous thrombosis after AstraZeneca vaccination

Norwegian and Danish researchers published a register study in BMJ of over 281,000 people who have received the AstraZeneca vaccine. – The study confirms previous findings from OUS and internationally. The registry study finds 11 additional cases of venous thrombosis among 100,000 vaccinated.   The article that follows people who have received the AstraZeneca vaccine in

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New Cell Atlas of COVID Lungs Reveals Why SARS-CoV-2 Is Deadly and Different

A new study is drawing the most detailed picture yet of SARS-CoV-2 infection in the lung, revealing mechanisms that result in lethal COVID-19, and may explain long-term complications and show how COVID-19 differs from other infectious diseases. Led by researchers at Columbia University Vagelos College of Physicians and Surgeons and Herbert Irving Comprehensive Cancer Center, the study found

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SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination and following lymphopenia

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is highly contagious and causes lymphocytopenia, but the underlying mechanisms are poorly understood. In this paper published on Nature fresearchers of Laboratory of Cell Engineering, Institute of Biotechnology, Beijing, China demonstrate that heterotypic cell-in-cell structures with lymphocytes inside multinucleate syncytia are prevalent in the lung tissues

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Three peptides could be causing severe COVID-19 complications: proteolytic storm induces bradykinin disregulation

A study published in July 2020 hypothesized a link between the presence of bradykinin, a well-known peptide, and severe cases of COVID-19. Vardan Karamyan, Ph.D., an associate professor and vice chair for the Texas Tech University Health Sciences Center (TTUHSC) Jerry H. Hodge School of Pharmacy Department of Pharmaceutical Sciences, had not previously conducted or

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A comprehensive guide to understand how SARS-CoV-2 enters the body and drugs that could mitigate infection

In the search for treatments for COVID-19, many researchers are focusing their attention on a specific protein that allows the virus to infect human cells. This protein, which cells carry on their surface, is called angiotensin converting enzyme 2 (ACE2) and provides the entry point for the coronavirus to enter cells. ACE2 is present in

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COVID-19-associated coagulopathy and antithrombotic agents—lessons after 1 year

COVID-19 is associated with a high incidence of thrombotic complications, which can be explained by the complex and unique interplay between coronaviruses and endothelial cells, the local and systemic inflammatory response, and the coagulation system. Empirically, an intensified dose of thrombosis prophylaxis is being used in patients admitted to hospital with COVID-19 and several guidelines

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