PRECISION MEDICINE – Page 3 – REGENHEALTHSOLUTIONS (RHS)

PIER MARIA FORNASARI
2020-02-03

Mesoblast submits Ryoncil’s completed biologics license application to US FDA for the treatment of children with steroid-refractory acute graft versus host disease (SR-aGVHD).

Mesoblast Limited today announced that it has submitted its completed Biologics License Application (BLA) to the United States Food and Drug Administration (US FDA) for Ryoncil™ (remestemcel-L), its lead allogeneic cell therapy for the treatment of children with steroid-refractory acute graft versus host disease (SRaGVHD). Mesoblast filed the final module of the rolling BLA submission,

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PIER MARIA FORNASARI
2020-01-30

Stem Cells, CRISPR and Gene Sequencing Technology are Basis of New Brain Cancer Model

Using genetically engineered human pluripotent stem cells, University of California San Diego School of Medicine researchers created a new type of cancer model to study in vivo how glioblastoma, the most common and aggressive form of brain cancer, develops and changes over time. “We have developed stem cell models that are CRISPR-engineered to have tumor-associated driver mutations

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PIER MARIA FORNASARI
2020-01-24

A single number helps Stanford data scientists find most dangerous cancer cells

Stanford data scientists have shown that figuring out a single number can help them find the most dangerous cancer cells. Biomedical data scientists at the Stanford University School of Medicine have shown that the number of genes a cell uses to make RNA is a reliable indicator of how developed the cell is, a finding that could

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PIER MARIA FORNASARI
2020-01-23

New Technique Predicts Which Melanoma Patients Are at Risk for Cancer Recurrence and Spread

Primary melanoma patients with lower T-cell fraction are 2.5 times more likely to have cancer metastasize than patients with higher T-cell fraction For most patients, melanoma begins with a small, pigmented spot on their skin that they notice starts to change. Many primary melanomas can be cured by having this lesion removed, but melanoma can

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PIER MARIA FORNASARI
2020-01-23

Discovery of new T-cell raises prospect of ‘universal’ cancer therapy

Researchers at Cardiff University have discovered a new type of killer T-cell that offers hope of a “one-size-fits-all” cancer therapy. T-cell therapies for cancer – where immune cells are removed, modified and returned to the patient’s blood to seek and destroy cancer cells – are the latest paradigm in cancer treatments. The most widely-used therapy,

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PIER MARIA FORNASARI
2020-01-17

B cells: New allies in sarcoma immunotherapy?

Source INSERM press room How can we improve and better personalize the treatment of soft tissue sarcomas, these particularly resistant and aggressive forms of cancer? An international team led by Wolf Hervé Fridman with researchers from Inserm, Sorbonne Université and Université de Paris at the Cordeliers Research Center, in collaboration with the French League against

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PIER MARIA FORNASARI
2020-01-16

Mutations in donors’ stem cells may cause problems for transplanted patients

A new study from Washington University School of Medicine in St. Louis suggests that bone marrow — or blood stem cells — from healthy donors can harbor extremely rare mutations that can cause health problems for the cancer patients who receive them. Such stem cell transplants are important for treating blood cancers, including acute myeloid

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PIER MARIA FORNASARI
2020-01-10

Nanoparticles deliver ‘suicide gene’ therapy to pediatric brain tumors growing in mice

Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a “suicide gene” to pediatric brain tumor cells implanted in the brains of mice. The poly(beta-amino ester) nanoparticles, known as PBAEs, were part of a treatment that also used a drug to kill the cells and prolong the test

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PIER MARIA FORNASARI
2020-01-08

Melanoma Immunotherapy Enhanced by Targeting Treg Cell Control Protein

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a new potential strategy for boosting the immune system’s ability to fight cancer. Studies in gene knockout mice, carried out in collaboration with a team at NYU Langone’s Perlmutter Cancer Center, suggested that a protein known as Siah2 is involved in the control of T

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PIER MARIA FORNASARI
2020-01-08

Immune cell discovery opens door to new powerful cancer therapies

Scientists at UCL have identified how a subset of immune cells are activated to kill cancerous cells, a finding in mice which could hold the key to new powerful therapies against cancer. This new study built on previous research*, also led by Professors Sergio Quezada and Karl Peggs (both UCL Cancer Institute), which found that

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REGENERATIVE AND PERSONALISED MEDICINE

DIGITAL HEALTHCARE

Category PRECISION MEDICINE

Mesoblast submits Ryoncil’s completed biologics license application to US FDA for the treatment of children with steroid-refractory acute graft versus host disease (SR-aGVHD).

Stem Cells, CRISPR and Gene Sequencing Technology are Basis of New Brain Cancer Model

A single number helps Stanford data scientists find most dangerous cancer cells

New Technique Predicts Which Melanoma Patients Are at Risk for Cancer Recurrence and Spread

Discovery of new T-cell raises prospect of ‘universal’ cancer therapy

B cells: New allies in sarcoma immunotherapy?

Mutations in donors’ stem cells may cause problems for transplanted patients

Nanoparticles deliver ‘suicide gene’ therapy to pediatric brain tumors growing in mice

Melanoma Immunotherapy Enhanced by Targeting Treg Cell Control Protein

Immune cell discovery opens door to new powerful cancer therapies