Archives: 2026-03-05

Cloaked Stem Cells Evade Immune Rejection in Mice, Pointing to a Potential Universal Donor Cell Line

A study published today in Stem Cell Reports demonstrates that genetically engineered human pluripotent stem cells (hPSCs) can overcome immune rejection in mice with humanized immune systems, surviving for five months in a stringent transplantation model. The findings provide proof-of-principle for the development of a potential universal donor hPSC line designed to resist immune attack. Led by Danny Chan,

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From Longevity to Cancer: Understanding the Dual Nature of Polyamines

Study reveals how the same molecules that promote healthy aging can fuel cancer growth through distinct molecular pathways Polyamines, a group of naturally occurring molecules found in all living organisms, are essential for fundamental cellular processes, such as growth and differentiation. In recent years, these compounds (particularly spermidine) have gained attention as promising ‘geroprotectors’ that

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Healthy Versions of Low-Carb and Low-Fat Diets Linked to Better Cardiovascular and Metabolic Health

The quality of a low-carbohydrate or low-fat diet may matter more than the amount of carbohydrates or fat consumed when it comes to reducing heart disease risk, according to a study published Feb. 11 in JACC. Researchers found that versions of both diet patterns emphasizing macronutrients from healthy foods were associated with a lower risk of

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Results of Phase 2b Clinical Trial Demonstrating Stem Cell Therapy Improved Condition of Patients with Age-Related Frailty Published in Cell Stem Cell

Longeveron Inc., a clinical stage biotechnology company developing regenerative cell therapy for life-threatening rare pediatric and chronic aging-related conditions, announced that results of its Phase 2b clinical trial were published today in Cell Stem Cell, a Cell Press Journal. The Phase 2b results demonstrated that intravenous laromestrocel, a mesenchymal stem cell product, improved the physical condition

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It is estimated that 6 out of 10 women in the US will have at least one type of cardiovascular disease by 2050.

Key aspects of the statement: Due to rising rates of high blood pressure , nearly 6 out of 10 women in the U.S. will have some form of cardiovascular disease (CVD) within the next 25 years, according to a new scientific statement published today in Circulation , the leading peer-reviewed scientific journal of the American Heart Association, a global organization working to transform

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AI opens a new era in the early detection of cancer and rare diseases

Autonomous systems and advanced language models have successfully identified complex injuries and disorders with unprecedented accuracy, enabling faster diagnoses and improving the chances of treatment and cure. Medicine faces a challenge that defines the fate of millions: detecting diseases before they progress. In this arena, time makes the difference between life and death, between a simple treatment

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Scientists of University of California San Francisco Find a Mechanism for How Exercise Protects the Brain

CSF study finds that an exercise-induced liver protein strengthens the blood-brain barrier, improving memory and slowing age-related decline. Researchers at UC San Francisco have discovered a mechanism that could explain how exercise improves cognition by shoring up the brain’s protective barrier of blood vessels. With age, this network of blood vessels — called the blood-brain

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