A single-cell study in Science reveals major shifts in immune cells, genome organization and gene regulation in the aging human hippocampus. These findings offer critical insights into brain aging with major implications for age-related dementias. Researchers have discovered that the human brain undergoes widespread age-related changes in genome regulation beginning in midlife that may help explain why
PANXEON, which combines multiple biomarkers, also identified a precancerous condition of the pancreas, potentially opening a path to intervention before invasive cancer develops One reason pancreatic cancer remains so deadly is because it’s usually discovered late, after it has spread. Now, a major new study shows that a blood test developed by researchers led by
You probably don’t think twice about putting on your socks – until your back makes it the hardest part of getting dressed. When ordinary movements become painful, even a little relief can matter. A new clinical trial suggests some of that relief could come from a surprisingly old-fashioned source: a soft belt wrapped around the lower back.
New recommendations based on extensive public engagement set out how the NHS could give patients faster access to AI advances with proportionate safeguards to protect patient safety and maintain high levels of trust. The National Commission into the Regulation of AI in Healthcare has today, 10 September 2026, published its recommendations on how the UK
New research paves way for novel therapies to reverse heart failure. Pioneering research by experts at the University of Sydney, the Baird Institute and the Royal Prince Alfred Hospital in Sydney has shown that heart muscle cells regrow after a heart attack, opening up the possibility of new regenerative treatments for cardiovascular disease. Following the
Analysis of data from 134 countries and territories shows wide differences between officially reported COVID-19 mortality rates and estimates based primarily on excess mortality. Official COVID-19 death figures in many countries differed significantly from estimates based primarily on excess mortality. Ariel Karlinsky of Hebrew University and Professor Moses Shayo of Hebrew University and King’s College London
A review led by University of Miami researchers examines how delivering stem cells directly into brain-supplying arteries could support recovery after ischemic stroke and identifies the evidence still needed before the approach becomes part of standard care. Key Takeaways Researchers from the University of Miami Miller School of Medicine and collaborating institutions have published a
Novartis announced positive topline results from its Phase III REMODEL-1/-2 trials of remibrutinib in relapsing multiple sclerosis.1 Remibrutinib, a highly selective and potent oral Bruton’s tyrosine kinase (BTK) inhibitor, demonstrated superiority versus teriflunomide in reducing annualized relapse rate (ARR) and inflammatory brain lesions with a favorable safety profile. The results of the REMODEL trials establish remibrutinib
First and only combination regimen to demonstrate statistically significant and clinically meaningful improvements in RFS and DMFS compared to KEYTRUDA alone for these patients in the adjuvant melanoma setting The Companies plan to present data at an upcoming international medical meeting and will engage with regulators on filing submissions for intismeran autogene in combination with
Ultra thin, flexible interface locates alternative signal pathways to bypass affected area Researchers from Houston Methodist and the University of Cambridge have developed a flexible device that wraps around the spinal cord and can simultaneously interpret multiple signals related to movement, sensation and internal body functions. The research demonstrates that a single device may be
