CHIP trial extends shelf life compared with conventional room-temperature storage Key Takeaways Extending the shelf life of platelets with refrigeration didn’t hurt their hemostatic function for people undergoing complex cardiac surgery, the landmark CHIPS trial found. Platelets stored at 1-6°C (33.8-42.8°F) for up to 21 days were noninferior to platelets stored up to 7 days
The Lancet Diabetes & Endocrinology recently published a consensus piece on using GLP-1 medications for obesity in Europe. The paper, “Nutritional, Functional, and Psychological Considerations for Incretin-Based Therapies in Adults—an EASO, EFAD, and ECPO Consensus Statement“, aimed to provide guidance on best practices for clinicians prescribing obesity medications — but one could argue, it’s more likely to lead
In older women with adequate calcium intake receiving osteoporosis medications, calcium supplements did not provide additional improvements in hip bone mineral density (BMD) or bone strength. However, a low dietary protein intake was associated with reduced skeletal benefits of antiresorptive therapy. METHODOLOGY TAKEAWAY IN PRACTICE “[The study] findings do not support the routine use of CaS [calcium
Heart failure already affects more than 60 million people worldwide and is one of the leading causes of hospitalization among people over the age of 65. Although it is commonly associated with advanced cardiovascular disease, it actually develops over many years, often without symptoms. Authors of a new expert statement published in the European Heart
Although the relationship between caffeine and cardiovascular health is complex, the latest research indicates consuming up to 5 cups of caffeinated coffee per day (up to 400 mg of caffeine/day) is safe for most adults and may be linked to cardiovascular health benefits in some individuals, according to a new American Heart Association scientific statement.
Many fractures are early-warning signs of osteoporosis. Yet in everyday clinical care they often go unrecognized and undocumented as warning signs, according to a new nationwide Austrian study by the Complexity Science Hub (CSH) and the Ludwig Boltzmann Institute for Osteology (LBI Osteology). Men are affected more often. THE STUDY IN A NUTSHELL Osteoporosis, a
International expert group reframes arthroplasty and spinal fusion complications as a shared problem of implant fixation failure, and issues clinical recommendations for peri-operative bone health care. A new position statement from the International Osteoporosis Foundation’s (IOF) Committee of Scientific Advisors Fracture Working Group urges orthopaedic surgeons and bone health specialists to work together to assess and treat
Studies assess population health impacts of the guideline on dyslipidemia Key Takeaways The new American cholesterol guideline would not make more Americans statin users per se, but instead shift the profile of people who should initiate lipid-lowering therapy to those younger and lower risk, research indicated. Based on National Health and Nutrition Examination Survey (NHANES)
First oral PCSK9 inhibitor provides an additional treatment option for adults with hypercholesterolemia The U.S. Food and Drug Administration approved Lipfendra (enlicitide), the first oral inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9), as an adjunct to diet and exercise to reduce low-density lipoprotein cholesterol (LDL-C), or “bad” cholesterol, in adults with hypercholesterolemia, including those with heterozygous
Key Takeaways A blood test for the biomarker phosphorylated tau 217 (p-tau217) recently received federal clearance, but questions have emerged around the extent to which such tests can accurately predict whether a cognitively healthy individual will go on to develop cognitive impairment—a key symptom of Alzheimer’s disease. A new, international study involving researchers across three
